Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of biliary tract differentiation. CCA is the second most common primary liver tumour and the incidence is increasing worldwide. CCA has high mortality owing to its aggressiveness, late diagnosis and refractory nature. In May 2015, the "European Network for the Study of Cholangiocarcinoma" (ENS-CCA: www.enscca.org or www.cholangiocarcinoma.eu) was created to promote and boost international research collaboration on the study of CCA at basic, translational and clinical level. In this Consensus Statement, we aim to provide valuable information on classifications, pathological features, risk factors, cells of origin, genetic and epigenetic modifications and current therapies available for this cancer. Moreover, future directions on basic and clinical investigations and plans for the ENS-CCA are highlighted.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/nrgastro.2016.51 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Some thoughts about the "Consensus statement on smoking and vascular risk" from the Spanish Autonomous Societies of Hypertension and Vascular Risk.
Nefrologia (Engl Ed)
January 2025
Servicio de Nefrología, Hospital Universitario de Badajoz, Badajoz, Spain. Electronic address:
Smoking is a known preventable risk factor for vascular diseases. However, it is one of the most forgotten risks when we talk about its relationship with kidney disease. Following the publication of the "Consensus statement on smoking and vascular risk" promoted by the autonomous societies of hypertension and vascular risk of Spain, we consider that the nephrology community should be alerted about the deleterious effects of exposure to tobacco smoke and its consequences on renal damage.
View Article and Find Full Text PDFIndications for the addition of a patellofemoral joint arthroplasty following a previous unicondylar knee arthroplasty- a literature review and Delphi consensus.
Arch Orthop Trauma Surg
January 2025
Institute for Locomotion, Aix-Marseille University, Marseille, France.
Introduction: The aim of this study was to establish an international consensus statement on the indications for the addition of a patellofemoral joint arthroplasty (PFJA) in patients with a unicondylar knee arthroplasty (UKA) and symptomatic progression of patellofemoral compartment osteoarthritis.
Materials And Methods: A systematic review of the literature was conducted, and the results used to inform the development of a statement by an expert working group. This was then evaluated and modified, using a Delphi process, by members of the European Knee Society (EKS).
Expert consensus on the benefits of neuraminidase in conventional influenza vaccines: a Delphi study.
BMC Infect Dis
January 2025
Patient-Centered Research, Evidera, London, UK.
Background: Seasonal vaccination is the mainstay of human influenza prevention. Licensed influenza vaccines are regularly updated to account for viral mutations and antigenic drift and are standardised for their haemagglutinin content. However, vaccine effectiveness remains suboptimal.
View Article and Find Full Text PDFThe origin of color categories.
Proc Natl Acad Sci U S A
January 2025
Section on Perception, Cognition, Action, Laboratory of Sensorimotor Research, National Eye Institute, NIH, Bethesda, MD 20892.
To what extent does concept formation require language? Here, we exploit color to address this question and ask whether macaque monkeys have color concepts evident as categories. Macaques have similar cone photoreceptors and central visual circuits to humans, yet they lack language. Whether Old World monkeys such as macaques have consensus color categories is unresolved, but if they do, then language cannot be required.
View Article and Find Full Text PDFDecreased attenuation difference between non-contrast and portal-venous phases of CT predicts the ultrasonography-unspecified adnexal torsion.
Insights Imaging
January 2025
Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Objectives: To evaluate the value of contrast-enhanced CT in diagnosing ultrasonography-unspecified adnexal torsion (AT).
Methods: Surgically confirmed patients with painful pelvic masses (n = 165) were retrospectively collected from two institutes. Two senior radiologists independently reviewed the CT images and determined the Hounsfield unit difference between non-contrast vs portal venous phases (ΔHU) in both derivation and validation samples.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!