Superwarfarin poisoning is usually due to chronic occult small-dose exposures and can easily be misdiagnosed and may lead to serious complications. The diagnosis can be confirmed by a concordant history and analyses of blood and urine specimens with the liquid chromatography with tandem mass spectrometry (LC-MS/MS) technique. Several months of continuous treatment with high doses of daily oral vitamin K, as well as other supportive measures, are warranted, especially when repeated laboratory measurements to help predict the treatment period are not available. In this paper, a case of superwarfarin poisoning due to chronic repetitive occupational dermal exposure to commercial rodenticides is presented.
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http://dx.doi.org/10.4274/tjh.2015.0433 | DOI Listing |
Front Pharmacol
November 2024
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
J Forensic Leg Med
November 2024
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address:
Brodifacoum, a long-acting anticoagulant rodenticide, exerts inhibitory effects on blood coagulation factor synthesis, leading to abnormal clotting function and potential fatality. Poisoning of accidental exposure to brodifacoum is not rare, but death from brodifacoum poisoning can be largely avoided with timely and long-term effective treatments, consequently, forensic data on fatalities due to brodifacoum poisoning may be limited. This paper presents a case of brodifacoum-induced homicide, detailing the medial records and pathological changes observed in multiple organs.
View Article and Find Full Text PDFChem Res Toxicol
November 2024
Jesse Brown VA Medical Center and Department of Anesthesiology, University of Illinois College of Medicine in Chicago, Chicago, Illinois 60612, United States.
J Avian Med Surg
October 2024
School of Veterinary Medicine, Murdoch University, Murdoch, Western Australia 6151, Australia.
Environ Pollut
October 2024
Service of Toxicology and Forensic Veterinary Medicine, Department of Health Sciences, Faculty of Veterinary Medicine, Campus de Espinardo, Universidad de Murcia, 30100, Murcia, Spain; Toxicology and Risk Assessment Research Group, IMIB-Pascual Parrilla, University of Murcia, 30120 El Palmar, Spain.
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