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| http://dx.doi.org/10.4103/0022-3859.180577 | DOI Listing |
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Balo concentric sclerosis, an emerging variant of multiple sclerosis: A case-series and literature review.
J Neuroimmunol
January 2025
School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:
Introduction: Balo concentric sclerosis (BCS) is a rare demyelinating disease. This study aims to follow up on patients initially diagnosed with BCS and MS or presented with BCS in the context of MS.
Methods: This study was conducted at an MS clinic center in Isfahan, monitoring 2600 MS patients, among which 10 cases were related to BCS.
Tissue Is the Issue: The Diagnosis of Butterfly Brain Lesions.
Cureus
December 2024
Neurology, Palmetto General Hospital, Hialeah, USA.
The corpus callosum can reveal a "butterfly" pattern on imaging in various conditions, including glioblastoma, primary central nervous system lymphoma, tumefactive multiple sclerosis, and toxoplasmosis. Early differentiation among these conditions is crucial to avoid aggressive treatments. In one case, a 70-year-old woman with a history of multiple sclerosis experienced a neurological decline.
View Article and Find Full Text PDFDeep learning MRI models for the differential diagnosis of tumefactive demyelination versus -wildtype glioblastoma.
AJNR Am J Neuroradiol
January 2025
From the Department of Radiology (GMC, MM, YN, BJE), Department of Quantitative Health Sciences (PAD, MLK, JEEP), Department of Neurology (CBM, JAS, MWR, FSG, HKP, DHL, WOT), Department of Neurosurgery (TCB), Department of Laboratory Medicine and Pathology (RBJ), and Center for Multiple Sclerosis and Autoimmune Neurology (WOT), Mayo Clinic, Rochester, MN, USA; Dell Medical School (MFE), University of Texas, Austin, TX, USA.
Background And Purpose: Diagnosis of tumefactive demyelination can be challenging. The diagnosis of indeterminate brain lesions on MRI often requires tissue confirmation via brain biopsy. Noninvasive methods for accurate diagnosis of tumor and non-tumor etiologies allows for tailored therapy, optimal tumor control, and a reduced risk of iatrogenic morbidity and mortality.
View Article and Find Full Text PDFCNS B cell infiltration in tumefactive anti-myelin oligodendrocyte glycoprotein antibody-associated disease.
Mult Scler J Exp Transl Clin
December 2024
Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan.
Background: Few studies have examined B cells among patients with anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD), including brain pathology.
Objective: To describe cases of tumefactive MOGAD with B-cell dominant central nervous system (CNS) infiltration.
Methods: In this study, we reviewed three cases with clinical and brain histopathological features with tumefactive MOGAD.
Establishment of an MRI-based radiomics model for distinguishing between intramedullary spinal cord tumor and tumefactive demyelinating lesion.
BMC Med Imaging
November 2024
School of Medicine, Southeast University, Nanjing, China.
Objective: Differentiating intramedullary spinal cord tumor (IMSCT) from spinal cord tumefactive demyelinating lesion (scTDL) remains challenging with standard diagnostic approaches. This study aims to develop and evaluate the effectiveness of a magnetic resonance imaging (MRI)-based radiomics model for distinguishing scTDL from IMSCT before treatment initiation.
Methods: A total of 75 patients were analyzed in this retrospective study, comprising 55 with IMSCT and 20 with scTDL.
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