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Ulcerative Colitis-associated Cancer/Dysplasia Detected Using Surveillance Colonoscopy Performed in the Clinical Remission Phase: A Report of Five Cases. | LitMetric

AI Article Synopsis

  • * To prevent cancer development, patients need effective medical therapy that targets both symptoms and chronic inflammation.
  • * Early cancer can emerge as soon as four years after ulcerative colitis diagnosis, so patients with unresolved inflammation should undergo vigilant surveillance colonoscopy.

Article Abstract

We herein report five cases of ulcerative colitis-associated cancer/dysplasia. Although clinical remission had been achieved in all patients, mucosal inflammation had been resolved in only one patient. Thus, in order to prevent cancer from developing, appropriate medical therapy aiming not only to relieve the clinical symptoms, but also to suppress chronic inflammation appears to be necessary. Moreover, cancer occurred as early as 4 years after the diagnosis in one patient. In patients without complete resolution of mucosal inflammation, careful surveillance colonoscopy should be initiated in the early phase.

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http://dx.doi.org/10.2169/internalmedicine.55.5714DOI Listing

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