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Life-Threatening MOG Antibody-Associated Hemorrhagic ADEM With Elevated CSF IL-6.
Neurol Neuroimmunol Neuroinflamm
July 2024
From the UCSF Weill Institute for Neurosciences (A.V., C.E.M., C.M.S., M.S., B.A.C., E.W., S.S.Z.), University of California, San Francisco; University of Nevada Reno School of Medicine (S.E.); Renown Health (L.M.G.), Reno, NV; Department of Radiology and Biomedical Imaging (E.G.); and Program in Immunology (S.S.Z.), University of California, San Francisco.
Acute disseminated encephalomyelitis (ADEM) is one characteristic manifestation of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). A previously healthy man presented with retro-orbital headache and urinary retention 14 days after Tdap vaccination. Brain and spine MRI suggested a CNS demyelinating process.
View Article and Find Full Text PDFCOVID-19 and neurologic manifestations: a synthesis from the child neurologist's corner.
World J Pediatr
June 2022
Department of Neurology, Hospital Dr. Exequiel González Cortés, Gran Avenida José Miguel Carrera 3300, 8900085, Santiago, Región Metropolitana, Chile.
Background: Since December 2019, the SARS-CoV-2 virus has been a global health issue. The main clinical presentation of this virus is a flu-like disease; however, patients with diverse neurologic manifestations have also been reported. In this review, we attempt to summarize, discuss and update the knowledge of the neurologic manifestations in the pediatric population affected by SARS-CoV-2 infection and the pandemic's effects in children with neurologic diseases.
View Article and Find Full Text PDFTherapeutic plasma exchange in clinical pediatric neurology practice: Experience from a tertiary referral hospital.
Clin Neurol Neurosurg
August 2021
Department of Pediatric Intensive Care, Ankara University Faculty of Medicine, Ankara, Turkey. Electronic address:
Objective: This study aims to retrospectively evaluate the long-term efficacy, tolerability, and safety of therapeutic plasma exchange (TPE) in children with various neuroimmunological disorders.
Methods: This analysis was a single-center, retrospective cohort study of pediatric patients with neuroimmunological events undergoing TPE procedures in a tertiary referral center.
Results: There were 23 patients, 14 boys (60.
Neurological Manifestations of Scrub Typhus: A Case Series from Tertiary Care Hospital in Southern East Rajasthan.
Ann Indian Acad Neurol
May 2019
Department of Neurology, Government Medical College, Kota, Rajasthan, India.
Scrub typhus is an acute febrile infectious illness caused by rickettsia species . In recent years, scrub typhus has reemerged as a life-threatening disease in India Scrub typhus has diverse clinical manifestations ranging from a nonspecific febrile illness to severe multiorgan dysfunction, and neurological complications are also common. Spectrum of neurological complications varies from common complications such as aseptic meningitis, meningoencephalitis and cerebellitis to rare complications such as myelitis, cerebral hemorrhage, acute disseminated encephalomyelitis (ADEM), and cerebral infarction.
View Article and Find Full Text PDFCytomegalovirus associated severe pneumonia in three liver transplant recipients.
J Infect Dev Ctries
November 2020
Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Inonu University, Malatya, Turkey.
Introduction: Cytomegalovirus (CMV), is the most common opportunistic infection, remains a cause of life-threatening disease and allograft rejection in liver transplant (LT) recipients. The purpose of this case series is to state that CMV may lead to severe pneumonia along with other bacteria.
Methodology: CMV pneumonia was diagnosed with the thoracic computed tomography (CT) scan findings, bronchoscopic biopsy, real time quantitative Polymerase Chain Reaction (qPCR) and clinical symptoms.
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