Background: Most total knee arthroplasty systems allow a degree of femoro-tibial component size mismatch. We aim to investigate the influence of size mismatch on outcome after primary total knee arthroplasty.
Methods: We reviewed 332 patients with cruciate-retaining Genesis II total knee arthroplasty with regard to femoro-tibial component size mismatch and Oxford Knee Score (OKS). We evaluated effects of Body Mass Index, gender and patellar procedure. Minimum follow-up is five years. We divided patients into four groups (tibial component larger than femoral component, no mismatch, femoral component one size larger and femoral component two sizes larger than tibial component).
Results: There was no statistically significant difference in OKS between the four groups. Size mismatch did not have a statistical significant effect on OKS in a multivariate analysis. Women had mismatched components in 66% of all cases and men in 40% of all cases.
Conclusions: Our study showed no statistically significant effect of femoro-tibial size mismatch on outcome after total knee replacement. Compared to men, women tend to have more component size mismatch.
Level Of Evidence: Level III, retrospective comparative study.
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http://dx.doi.org/10.1016/j.knee.2016.03.003 | DOI Listing |
Nanoscale
January 2025
Department of Materials Science and Engineering, Kyushu Institute of Technology, 1-1 Sensui-cho, Tobata-ku, Kitakyushu 804-8550, Japan.
Self-organization realizes various nanostructures to control material properties such as superconducting vortex pinning and thermal conductivity. However, the self-organization of nucleation and growth is constrained by the growth geometric symmetry. To realize highly controlled three-dimensional nanostructures by self-organization, nanostructure formation that breaks the growth geometric symmetry thermodynamically and kinetically, such as tilted or in-plane aligned nanostructures, is a challenging issue.
View Article and Find Full Text PDFJ Cardiovasc Dev Dis
January 2025
Department of Neurology, University Hospital in Ostrava, 70800 Ostrava, Czech Republic.
The e-STROKE study is a prospective, multicenter observational study designed to assess the impact of various CT parameters (including e-ASPECT, CT perfusion (CTP), collateral flow status, and the size and location of the ischemic lesion) on the clinical outcomes of patients with ischemic stroke, as evaluated by the modified Rankins Scale (mRS) three months post-stroke. This study also aims to investigate whether the use of multimodal CT imaging increases the number of patients eligible for recanalization therapy. The analysis will integrate data from the RES-Q registry and radiological data from the e-STROKE system provided by Brainomix Ltd.
View Article and Find Full Text PDFInt J Cardiol Heart Vasc
February 2025
Faculty of Medicine, Tanta University, Tanta, Egypt.
Background: Aortic stenosis (AS) remains a prevalent and serious global health concern, exacerbated by an aging population worldwide. This valvular disease, when symptomatic and without appropriate intervention, severe AS can drastically reduce life expectancy. In our systematic review and -analysis, we aim to synthesize available evidence to guide clinical decision-making by comparing the performance of TAVR and SAVR, specifically in patients with severe AS and a small aortic annulus.
View Article and Find Full Text PDFNat Struct Mol Biol
January 2025
Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA.
Fascin cross-links actin filaments (F-actin) into bundles that support tubular membrane protrusions including filopodia and stereocilia. Fascin dysregulation drives aberrant cell migration during metastasis, and fascin inhibitors are under development as cancer therapeutics. Here, we use cryo-EM, cryo-electron tomography coupled with custom denoising and computational modeling to probe human fascin-1's F-actin cross-linking mechanisms across spatial scales.
View Article and Find Full Text PDFGac Med Mex
January 2025
School of Medicine, Pontificia Universidad Javeriana.
Background: In Colombia, gastric cancer is fifth in incidence (12.8 cases per 100,000) and third in mortality (9.9 cases per 100,000).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!