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Change in body mass index among girls with precocious puberty under treatment. | LitMetric
Introduction : Changes in body mass index (BMI) among girls with idiopathic central precocious puberty (ICPP) under treatment have been controversial in other populations.Objective : To assess changes in BMI Z score and the rate of overweight and obesity in Mexican girls with ICPP during their first year of treatment.Methodology : A retrospective study was conducted among girls with ICPP under treatment with leuprolide, with a somatometry performed every six months, over a 1-year period. An analysis of variance (ANOVA) was done to establish differences in BMI Z score and a multivariate analysis was used to assess the relationship among the different factors.Results : Among 121 girls, BMI Z score increased from 0.87 to 1.32, and the rate of overweight and obesity increased from 40.5% to 70.3%, a statistically significant difference.Conclusions : Changes in BMI Z score and the rate of overweight and obesity among Mexican girls with ICPP increased significantly.
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