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Three new terpenes with potential antibacterial and anti-COVID-19 activities from the stems of R. Br.
Nat Prod Res
January 2025
School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
The extract of the stems of R. Br. yielded three new terpenes () including two diterpenes and one triterpene, named euryachins C-E, as well as three known diterpenes ().
View Article and Find Full Text PDFInduction of innate immunity and plant growth promotion in tomato unveils the antiviral nature of bacterial endophytes against groundnut bud necrosis virus.
J Virol
December 2024
Agriculture College and Research Institute, Kudumiyanmalai, Pudukottai, Tamil Nadu, India.
Tomato is an important crop worldwide, but groundnut bud necrosis virus (GBNV) often hampers its growth. This study investigates the antiviral potential of bacterial endophytes, including CNEB54, CNEB4, CNEB26, and BAVE5 against GBNV, as well as their ability to enhance immunity and growth in tomato. All four bacterial isolates demonstrated a significant delay in GBNV symptom development 10 days post-inoculation, with disease incidence ranging from 18% to 36% compared to 84% in control.
View Article and Find Full Text PDFAPC 4099 has broad-spectrum antimicrobial activity against both bacteria and fungi and produces several antimicrobial peptides, including the novel circular bacteriocin safencin E.
Appl Environ Microbiol
December 2024
School of Microbiology, University College Cork, Cork, County Cork, Ireland.
Unlabelled: APC 4099, isolated from bees' gut, has been identified as a promising candidate for food biopreservation. Antimicrobial activity screening revealed a broad-spectrum inhibition potential, ranging from gram-positive pathogenic bacteria to fungi responsible for food spoilage. Genomic analysis identified biosynthetic gene clusters coding for several antimicrobial peptides and secondary metabolites.
View Article and Find Full Text PDFImpact of the probiotic on loperamide-induced delayed bowel movement in Sprague-Dawley rats.
Food Funct
January 2025
Institute of Human Behavior & Genetics, Korea University, Seoul 02841, Republic of Korea.
This study investigated the effects of on alleviating loperamide-induced constipation. To evaluate the efficacy of in Sprague-Dawley (SD) rats, fecal parameters, the intestinal transit rate, and changes in intestinal mucosal cells were measured through histological analysis. Additionally, serotonin levels, water absorption, tight junction-related gene expression, and the cecal short-chain fatty acid (SCFA) content were analyzed.
View Article and Find Full Text PDFChemical Composition, Antimicrobial, and Enzyme Inhibitory Properties of Elaeagnus angustifolia L.
Chem Biodivers
January 2025
Ataturk Universitesi, Chemistry, Yakutiye, 25440, Türkiye, 25440, Erzurum, TURKEY.
Research on natural antioxidants derived from plants has surged due to their potential health benefits. In the current study, the chemical composition, enzyme inhibitory activity, and antimicrobial effects of the Elaeagnus angustifolia L. plant, including leaves, flowers, and flower stalks extracts, were analyzed.
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