The aim of this study was to answer the question "What do nursing home residents do themselves in order to maintain their dignity?" Twenty-eight residents, 8 men and 20 women, aged 62 to 103 years, from 6 different nursing homes in Scandinavia were interviewed. The results showed that the residents tried to expand their life space, both physical and ontological, in order to experience health and dignity.
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http://dx.doi.org/10.1097/HNP.0000000000000145 | DOI Listing |
Sci Rep
January 2025
Drug Theoretics and Cheminformatics Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700 032, India.
We have adopted the classification Read-Across Structure-Activity Relationship (c-RASAR) approach in the present study for machine-learning (ML)-based model development from a recently reported curated dataset of nephrotoxicity potential of orally active drugs. We initially developed ML models using nine different algorithms separately on topological descriptors (referred to as simply "descriptors" in the subsequent sections of the manuscript) and MACCS fingerprints (referred to as "fingerprints" in the subsequent sections of the manuscript), thus generating 18 different ML QSAR models. Using the chemical spaces defined by the modeling descriptors and fingerprints, the similarity and error-based RASAR descriptors were computed, and the most discriminating RASAR descriptors were used to develop another set of 18 different ML c-RASAR models.
View Article and Find Full Text PDFJ Sci Med Sport
December 2024
Faculty of Education, University of the Ryukyus, Japan.
Objectives: To examine the validity and reliability of the Simple Motor Competence-check for Kids (SMC-Kids), which was developed to assess motor development in preschool children.
Design: A cross-sectional and repeated-measures design.
Methods: To assess validity, 71 children aged 4-6 years completed the Test of Gross Motor Development-3 (TGMD-3) and SMC-Kids (10 m shuttle run and paper ball throw).
Ultrason Sonochem
December 2024
Hubei Key Laboratory of Edible Wild Plants Conservation & Utilization, College of Life Sciences, Hubei Normal University, Huangshi 435002, China; Hubei Engineering Research Center of Special Wild Vegetables Breeding and Comprehensive Utilization Technology, Hubei Normal University, Huangshi 435002, China. Electronic address:
The implementation of innovative techniques to achieve low-salt strategies in cured products is a critical issue faced by the food industry. This study aimed to investigate the impact of ultrasound treatment on the quality of the low-salt air-dried fish. The results showed that compared to traditional liquid curing, ultrasound-assisted curing significantly increased the NaCl transfer rate, improved tenderness, and improved water retention and in vitro digestibility (p < 0.
View Article and Find Full Text PDFPopul Space Place
April 2024
Population Research Centre, Faculty of Spatial Sciences, University of Groningen, Groningen, The Netherlands
There are well-documented associations between life course changes and migration; yet, the occurrence, order, and timing of reasons for migrating are growing increasingly diverse. Migration following adverse life events, such as a divorce or an involuntary job loss, may be qualitatively distinct from migration undertaken for other reasons. Moves, especially long-distance moves, following adverse life events, may be defined more by seeking family and familiar locations.
View Article and Find Full Text PDFACS Synth Biol
January 2025
Faculty of Biosciences, Fisheries and Economics, UiT─The Arctic University of Norway, 9019 Tromsø, Norway.
The choice of organism to host a genetic circuit, the chassis, is often defaulted to model organisms due to their amenability. The chassis-design space has therefore remained underexplored as an engineering variable. In this work, we explored the design space of a genetic toggle switch through variations in nine ribosome binding site compositions and three host contexts, creating 27 circuit variants.
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