AI Article Synopsis
Article Abstract
The Authors discuss the theoretical principles of the intra-arterial administration route of antineoplastic drug in the treatment of primaries or metastatic diseases.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Synergistic Anti-Cancer Effects of Isocnicin and Radiotherapy in Glioblastoma: A Natural Compound's Potential.
Biomedicines
December 2024
Laboratory of Pharmacognosy, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Background/objectives: Glioblastoma (GBM) is the most aggressive type of brain tumor in adults. Currently, the only treatments available are surgery, radiotherapy, and chemotherapy based on temozolomide (TMZ); however, the prognosis is dismal. Several natural substances are under investigation for cancer treatment.
View Article and Find Full Text PDFPhase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural carcinosis.
Cancer Treat Res Commun
December 2024
Division of Thoracic Surgery, University Hospital of Lausanne, Rue du Bugnon 46 1011, Lausanne, Switzerland. Electronic address:
Background: Pleural carcinosis originates from various cancers. Its management consists in systemic therapies combined to dyspnea relief procedures. Prior studies have tested hyperthermic intrathoracic chemotherapy to treat pleural carcinosis with interesting patient survival results.
View Article and Find Full Text PDFAn Assessment of Surface Contamination and Dermal Exposure to 5-Fluorouracil in Healthcare Settings by UPLC-MS/MS Using a New Atmospheric Pressure Ionization Source.
Toxics
October 2024
Centre for Environment and Health, Department of Public Health and Primary Care, University of Leuven (KU Leuven), 3000 Leuven, Belgium.
5-Fluorouracil (5-FU) is a well-known cytostatic drug, which is often used in cancer treatments. Yet, it is also a very dangerous compound for people who are occupationally exposed to it for a long time, such as pharmacy employees, nurses and cleaning staff. We aimed to improve and implement a LC-MS/MS method for 5-FU quantification on surface contamination samples collected with swabs in a pharmacy department and outpatient nursing station of a university hospital.
View Article and Find Full Text PDFPharmaceuticals in the environment: A strategy for prioritizing molecules of environmental concern.
Chemosphere
November 2024
Laboratory of Integrated Sciences, Universidade Federal de São Paulo, Diadema, SP, CEP 09972-270, Brazil; Department of Environmental Sciences, Laboratory of Ecology and Nature Conservancy (LECON), Group of Landscape Ecology and Conservation Planning (LEPLAN), Universidade Federal de São Paulo, Diadema, CEP 09972-270, Brazil; Antimicrobial Resistance Institute of São Paulo (ARIES), São Paulo, Brazil. Electronic address:
Article Synopsis
- * The proposed strategy focuses on antineoplastics with low biodegradability and significant ecological risks, utilizing data from São Paulo, Brazil, to predict the mass of these drugs entering waterways and creating a prioritization index based on multiple risk factors.
- * Key prioritized antineoplastics identified include Paclitaxel and Cisplatin, highlighting the strategy's versatility for adapting to different contexts and improving drug environmental impact assessments.
Article Synopsis
- Despite advancements in anti-cancer therapies leading to higher cure rates for early-stage breast cancer, chemotherapy remains the primary treatment, often causing cardiovascular complications.* -
- Many breast cancer patients, particularly those over 50, already have cardiovascular risk factors, and chemotherapy can worsen this by altering lipid levels in the body.* -
- The study aims to highlight the negative impact of chemotherapy-induced dyslipidemia on breast cancer outcomes and the associated risk of developing cardiovascular diseases.*
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!