AI Article Synopsis
- Influenza remains a serious public health issue in the U.S., causing over 200,000 hospitalizations and 30,000-50,000 deaths annually despite advancements in vaccine and virus research.
- Quick and accurate diagnosis of influenza is crucial for starting antiviral treatment early, which can help reduce illness and death during both seasonal outbreaks and pandemics.
- Various diagnostic methods exist for detecting influenza, including viral culture, immunofluorescence assays, nucleic acid tests, and rapid tests, with ongoing developments aimed at improving these techniques.
Article Abstract
Despite significant advancement in vaccine and virus research, influenza continues to be a major public health concern. Each year in the United States of America, influenza viruses are responsible for seasonal epidemics resulting in over 200,000 hospitalizations and 30,000-50,000 deaths. Accurate and early diagnosis of influenza viral infections are critical for rapid initiation of antiviral therapy to reduce influenza related morbidity and mortality both during seasonal epidemics and pandemics. Several different approaches are currently available for diagnosis of influenza infections in humans. These include viral isolation in cell culture, immunofluorescence assays, nucleic acid amplification tests, immunochromatography-based rapid diagnostic tests, etc. Newer diagnostic approaches are being developed to overcome the limitations associated with some of the conventional detection methods. This review discusses diagnostic approaches currently available for detection of influenza viruses in humans.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848591 | PMC |
| http://dx.doi.org/10.3390/v8040096 | DOI Listing |
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