AI Article Synopsis
- Cerebral blood flow is crucial for brain function and diagnoses various encephalopathies, yet its changes post-mild traumatic brain injury (TBI) are not well understood.
- The study utilized pulsed arterial spin labeling to observe that cerebral blood flow was highest in gray matter and lowest in white matter following mild TBI, with significant reductions in multiple brain regions during acute and subacute stages.
- Results indicated that while blood flow diminished in several areas after injury, it was restored during the chronic stage, highlighting the technique's potential for assessing TBI severity and recovery.
Article Abstract
Cerebral blood flow is strongly associated with brain function, and is the main symptom and diagnostic basis for a variety of encephalopathies. However, changes in cerebral blood flow after mild traumatic brain injury remain poorly understood. This study sought to observe changes in cerebral blood flow in different regions after mild traumatic brain injury using pulsed arterial spin labeling. Our results demonstrate maximal cerebral blood flow in gray matter and minimal in the white matter of patients with mild traumatic brain injury. At the acute and subacute stages, cerebral blood flow was reduced in the occipital lobe, parietal lobe, central region, subcutaneous region, and frontal lobe. Cerebral blood flow was restored at the chronic stage. At the acute, subacute, and chronic stages, changes in cerebral blood flow were not apparent in the insula. Cerebral blood flow in the temporal lobe and limbic lobe diminished at the acute and subacute stages, but was restored at the chronic stage. These findings suggest that pulsed arterial spin labeling can precisely measure cerebral blood flow in various brain regions, and may play a reference role in evaluating a patient's condition and judging prognosis after traumatic brain injury.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810989 | PMC |
| http://dx.doi.org/10.4103/1673-5374.177733 | DOI Listing |
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