AI Article Synopsis
- - Lipid mediators are crucial in managing skin inflammation, impacting processes like cell growth and death during inflammatory responses.
- - In skin diseases like acne, psoriasis, and atopic dermatitis, excessive lipid mediators contribute to their development and can significantly reduce patient quality of life.
- - Recent findings indicate that treatments targeting lipid mediators could potentially improve the management of these dermatological conditions.
Article Abstract
Lipid mediators play a main role in the complex course of cutaneous inflammatory reactions. They regulate a wide spectrum of cellular processes such as cell proliferation and apoptosis. In the early phase of inflammation, excessive amounts of lipid mediators are released and play a major role in the pathogenesis of skin diseases. Recent data suggest that lipid mediators are able to interfere with the pathogenesis of certain dermatologic diseases, seriously affecting patient quality of life. Acne, psoriasis, and atopic dermatitis are specific examples of skin diseases that may respond to treatment with medication affecting these metabolic pathways. The authors briefly present the current knowledge about the role of lipid mediators in common skin pathologies.
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