Objective: The aim of this study was to investigate the value of two quantitative indicators, the apparent diffusion coefficient (ADC) and the exponent apparent diffusion coefficient (EADC), of magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) in the differential diagnosis of ovarian epithelial tumors.
Materials And Methods: Clinical and MRI data from ovarian epithelial tumors were analyzed after pathology confirmation of 85 lesions from 76 cases (47 lesions from 41 benign cases; 38 lesions from 35 malignant cases). Patients underwent routine MRI examination and DWI before surgery. The average ADC and EADC values of the solid sections of the tumors were measured when the b value was 1000 s/mm 2.
Results: The mean ADC value of the solid sections in the benign group was 1.28 ± 0.23 × 10-3 mm 2/s; the average EADC value was 27.96 ± 5.78 × 10-2. In the malignant group, the mean ADC value of the solid sections was 0.86 ± 0.17 × 10-3 mm 2/s; the average EADC value was 42.37 ± 5.96 × 10-2. When the b value was 1000 s/mm 2, there was a statistically significant difference in ADC and EADC values between benign and malignant ovarian tumors (P < 0.05).
Conclusion: ADC and EADC values of DWI can be used to differentiate benign and malignant ovarian epithelial tumors.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4103/0973-1482.163667 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Time-dependent diffusion MRI and kinetic heterogeneity as potential imaging biomarkers for diagnosing suspicious breast lesions with 3.0-T breast MRI.
Magn Reson Imaging
January 2025
Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 Da Hua Road, Dong Dan, Beijing 100730, PR China; Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, PR China.
Purpose: This study aimed to evaluate the diagnostic efficacy of time-dependent diffusion magnetic resonance imaging (td-dMRI) and dynamic contrast-enhanced MRI (DCE-MRI)-based kinetic heterogeneity in differentiating suspicious breast lesions (categorised as Breast Imaging Reporting and Data System 4 or 5).
Methods: This prospective study included 51 females with suspicious breast lesions who underwent preoperative breast MRI, including DCE-MRI and td-dMRI. Six kinetic parameters, namely peak, persistent, plateau, washout component, predominant curve type, and heterogeneity, were extracted from the DCE series using MATLAB and SPM software.
The Added Value of Apparent Diffusion Coefficient and Histogram Analysis in Assessing Treatment Response of Locally Advanced Cervical Cancer.
J Comput Assist Tomogr
November 2024
From the Diagnostic Radiology Department, Faculty of Medicine, Mansoura University-Egypt, Mansoura, Egypt.
Objective: The aim of the study is to assess the diagnostic performance of quantitative analysis of diffusion-weighted imaging in assessing treatment response in cervical cancer patients.
Methods: A retrospective analysis was done for 50 patients with locally advanced cervical cancer who received concurrent chemoradiotherapy and underwent magnetic resonance imaging and diffusion-weighted imaging. Treatment response was classified into 4 categories according to RECIST criteria 6 months after therapy completion.
Prostate Cancer Risk Prediction Model Using Clinical and Magnetic Resonance Imaging-Related Findings: Impact of Combining Lesions' Locations and Apparent Diffusion Coefficient Values.
J Comput Assist Tomogr
November 2024
From the Department of Radiology, Mayo Clinic, Rochester, MN.
Objectives: The aims of the study are to develop a prostate cancer risk prediction model that combines clinical and magnetic resonance imaging (MRI)-related findings and to assess the impact of adding Prostate Imaging-Reporting and Data System (PI-RADS) ≥3 lesions-level findings on its diagnostic performance.
Methods: This 3-center retrospective study included prostate MRI examinations performed with clinical suspicion of clinically significant prostate cancer (csPCa) between 2018 and 2022. Pathological diagnosis within 1 year after the MRI was used to diagnose csPCa.
Diffusion weighted imaging for improving the diagnostic performance of screening breast MRI: impact of apparent diffusion coefficient quantitation methods and cutoffs.
Front Oncol
December 2024
Department of Radiology, School of Medicine, University of Washington, Seattle, WA, United States.
Introduction: Diffusion weighted MRI (DWI) has emerged as a promising adjunct to reduce unnecessary biopsies prompted by breast MRI through use of apparent diffusion coefficient (ADC) measures. The purpose of this study was to investigate the effects of different lesion ADC measurement approaches and ADC cutoffs on the diagnostic performance of breast DWI in a high-risk MRI screening cohort to identify the optimal approach for clinical incorporation.
Methods: Consecutive screening breast MRI examinations (August 2014-Dec 2018) that prompted a biopsy for a suspicious breast lesion (BI-RADS 4 or 5) were retrospectively evaluated.
Brain magnetic resonance imaging findings in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): A case-based review.
Radiol Case Rep
March 2025
Department of Radiology, Medical School, University of Ioannina, Stavros Niarchos Avenue, Ioannina 45500, Greece.
Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is a rare autosomal recessive disorder, manifesting with gastrointestinal dysmotility, cachexia, ptosis and peripheral neuropathy. Diffuse leukoencephalopathy in brain MRI is a hallmark of MNGIE. We report a case of a 21-year-old female with MNGIE, presenting with cachexia and chronic diarrhea.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!