AI Article Synopsis
- Fetal scalp blood sampling is rarely used due to its invasive nature, prompting the development of a portable oximetry device for assessing fetal oxygen levels.
- A study with mice using this new oximetry showed a strong correlation between fetal head tissue oxygen saturation and blood pH levels (r=0.90), reinforcing prior findings from human cases.
- The promising results suggest that this non-invasive method may become more popular among obstetricians for monitoring fetal health, particularly regarding acidosis during labor.
Article Abstract
Although fetal scalp blood sampling is an examination to assess fetal acidosis during the intrapartum period, it has not been widely used by obstetricians because of its invasiveness. We have developed a small, portable oximetry with a sensor attached to the examiner's finger. Our previous report using this oximetry concluded that fetal head tissue oxygen saturation (StO 2 StO2 ) correlated with umbilical cord artery blood pH. We investigated whether the association between StO 2 StO2 and blood pH in mice could be validated using this oximetry. Eleven the Institute for Cancer Research (ICR) mice were measured using a near-infrared spectroscopy probe at the craniofacial site in a closed polyethylene bag while changing the oxygen concentration. A total of nine blood samples were collected and analyzed for pH. The StO 2 StO2 and tissue blood pH showed a strong positive correlation (r=0.90 r=0.90 and P=0.0009 P=0.0009 ). The StO 2 StO2 and total hemoglobin index also showed a positive correlation (r=0.84 r=0.84 and P=0.0049 P=0.0049 ). Thus, the results of the present study support those of our previous report on clinical cases and allow examiners to easily check the status of fetal acidosis. Fetal management using this oximetry might gain popularity with obstetricians in the near future.
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| http://dx.doi.org/10.1117/1.JBO.21.4.040502 | DOI Listing |
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