Interfering with CCL5/CCR5 at the Tumor-Stroma Interface. | LitMetric

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Interfering with CCL5/CCR5 at the Tumor-Stroma Interface. | LitMetric

Interfering with CCL5/CCR5 at the Tumor-Stroma Interface.

Vincenzo Bronte Emilio Bria

Cancer Cell

Medical Oncology, Department of Medicine, Verona University Hospital, Verona 37134, Italy.

Published: April 2016

In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.ccell.2016.03.019	DOI Listing

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