Objective: To determine the importance of fasting calcium/creatinine ratio in patients with calcium stones and its relation with hypercalciuria and phospho-calcium metabolism.
Methods: Cross-sectional study including 143 patients divided into two groups according to fasting calcium/creatinine. Group 1: 66 patients (calcium/ creatinine<0.11); Group 2: 77 patients (calcium/ creatinine>0.11). A comparative study is performed between groups including phospho-calcium metabolism parameters and excretion of urinary lithogenic markers. Linear correlation studying calciuria and fasting calcium/ creatinine was performed. SPSS 17.0 statistical analysis software was used, considering p≤0.05.
Results: It is noteworthy that group 2 had increased 24 h urine calcium excretion in comparison to group 1 (229.3 vs 158.1; p=0.0001) and calcium/citrate (0.47 vs 0.34; p=0.001). There is a positive and significant correlation between calcium levels in 24 h urine and fasting calcium/creatinine (R=0.455; p=0.0001) and a cutoff is set at 0.127 (sensitivity 72%, specificity 66%) to determine hypercalciuria (>260 mg in 24 h).
Conclusion: Increased fasting calcium/creatinine determines increased 24 hours calcium excretion, although the sensitivity and specificity to determine hypercalciuria is not high.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Assessing the Impact of Serum Calcium, 25-Hydroxy Vitamin D, Ferritin, and Uric Acid Levels on Colorectal Cancer Risk.
J Clin Med Res
October 2024
Department of Pediatrics, University of Otago Christchurch, Christchurch, New Zealand.
Background: The aim of this study is to investigate whether vitamin D, calcium, ferritin, and uric acids play a beneficial biomarker role in the prevention of colorectal cancer (CRC) risk.
Methods: The case-control design was employed, including 650 CRC cases and 650 controls aged 35 to 70 years, comprising both men and women. The study encompasses sociodemographic data, clinical information, radiological diagnoses, and biochemical measurements.
Effects of lemon-tomato juice consumption on crystal formation in the urine of patients with calcium oxalate stones: A randomized crossover clinical trial.
Curr Urol
March 2023
Department of General Surgery, Government Medical College Konni, Kerala, India.
Background: Dietary supplementation with citrate-containing juices may serve as an effective alternative to potassium citrate therapy for preventing calcium oxalate stone recurrence. This study was performed to evaluate whether consumption of lemon-tomato juice can decrease the tendency for stone formation in the urine of calcium oxalate stone formers.
Materials And Methods: The study was conducted as a prospective interventional randomized crossover clinical trial with a repeated-measures design.
Modified Atkins diet for drug-resistant epilepsy and the risk of urolithiasis.
Pediatr Res
January 2022
Pediatric Neurology Unit, Department of Pediatrics, Faculty of Medicine Ain Shams University, Cairo, Egypt.
Background: Ketogenic diet (KD) is widely used for drug-resistant epilepsy (DRE). The study was designed to evaluate one of the risk factors for development of renal calculi with KD.
Methods: Twenty patients with DRE on Modified Atkins diet (MAD) were subjected to full history and laboratory investigations, including microscopic urine analysis, urinary calcium after overnight fasting, and calcium/creatinine ratio, as well as pelviabdominal ultrasound.
Prevalence of Infection among Type 2 Diabetes Mellitus.
Adv Biomed Res
July 2020
Department of Endocrinology, Medipol International School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Article Synopsis
- * Research involved 529 T2DM patients and 529 control participants, measuring antibody levels (IgG, IgA), along with various health parameters like fasting blood glucose and cholesterol levels.
- * Results indicated that T2DM patients had significantly higher antibody titers for infections and a greater prevalence of related symptoms, such as hypertension, vomiting, and gastrointestinal issues, compared to the control group.
Metabolic evaluation of patients with recurrent, multiple or bilateral renal stones in Jaffna.
Ceylon Med J
September 2020
University Surgical Unit, Teaching Hospital Jaffna, Sri Lanka.
Introduction: A comprehensive evaluation to identify metabolic abnormalities will help design management strategies for prevention of renal stone recurrences. The objective of this study is to identify the metabolic risk factors in a series of patients with recurrent, multiple or bilateral renal stone disease from the Northern Province, Sri Lanka.
Methods: This is a hospital based observational study on patients with recurrent, multiple or bilateral renal stones.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!