Toxoplasma gondii is a zoonotic obligatory intracellular protozoan parasite with the capability to infect all warm-blooded animals. One of the great concerns is that it can lead to ovine abortion in sheep growing industry. Different diagnostic methods such as serology, pathology, immunohistochemistry, bioassay and molecular detection have been used in order to detect ovine abortion associated with T. gondii. In this case, an outbreak of congenital toxoplasmosis based on serological, macroscopic, pathological detection and isolation of T. gondii by bioassay is described and emphasized on the importance of this route of transmission that caused lamb losses and an increase in possible sources of infection for human and environment.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815860 | PMC |
http://dx.doi.org/10.1007/s12639-014-0467-x | DOI Listing |
Cureus
December 2024
Obstetrics and Gynecology, Shalamar Medical and Dental College, Lahore, PAK.
Introduction Congenital malformations are a major cause of perinatal morbidity and mortality in developing countries and are assuming greater importance than ever before. They affect a variety of organ systems and various etiologies have been identified in literature including Toxoplasmosis, Other (syphilis, varicella-zoster, parvovirus B19), Rubella, Cytomegalovirus, Herpes Simplex (TORCH) infections, exposure to pollutants, consumption of tobacco and alcohol, and advanced maternal age. In developing countries, diagnosis is frequently delayed which leads to poorer outcomes.
View Article and Find Full Text PDFInt Arch Otorhinolaryngol
January 2025
School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Microtia and aural atresia present congenital ear anomalies that affect external ear and are associated with conductive hearing loss. Both anomalies result from exposure to various prenatal risk factors, most common during the first trimester of pregnancy. This study was aimed at epidemiological analysis of microtia/atresia and associated risk factors in the Kazakhstani population.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Pathogen Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
is a globally widespread pathogen of significant veterinary and medical importance, causing abortion or congenital disease in humans and other warm-blooded animals. Nevertheless, the current treatment options are restricted and sometimes result in toxic side effects. Hence, it is essential to discover drugs that demonstrate potent anti- activity.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, P.O. Box 80324, Jeddah 21589, Saudi Arabia.
Toxoplasmosis is an infection caused by the parasite and is considered asymptomatic in most cases. In pregnant women, however, the disease can be transmitted to the foetus, causing severe congenital consequences. Congenital toxoplasmosis can be avoided by practising simple preventive lifestyle measures during pregnancy.
View Article and Find Full Text PDFMicrob Pathog
January 2025
Tropical Projects, Hitchin, United Kingdom. Electronic address:
Background: Toxoplasma infections are highly prevalent worldwide and can cause serious complications in immunocompromised individuals and lead to congenital infections in neonates. Despite ongoing efforts to develop T. gondii vaccines, none have been developed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!