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Fungal Melanonychia: A Systematic Review.
Microorganisms
May 2024
Ibero-Latin American College of Dermatology (CILAD), Buenos Aires C1091, Argentina.
Article Synopsis
- * The study found that the majority of affected individuals were men, with a notable prevalence in Turkey, and common factors contributing to the condition included nail trauma and outdoor activities.
- * Clinical presentations varied, with 45% having a single affected nail and diverse melanonychia types observed, indicating a complex differential diagnosis for this uncommon variant of onychomycosis.
Various Free Flap Reconstruction Techniques after Hand and Foot Melanonychia Ablation: A Case Series.
J Clin Med
May 2024
Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul 13620, Republic of Korea.
Article Synopsis
- - The management of melanonychia, which can resemble nail melanoma, is debated, and surgical removal of the entire lesion is often necessary for accurate diagnosis and treatment.
- - Between 2020 and 2022, eleven patients underwent surgical procedures that involved total nail bed removal followed by immediate reconstruction using fasciocutaneous free flaps.
- - Histological analysis confirmed benign lesions in all cases post-surgery, with no complications aside from one instance of partial necrosis that healed, and there were no recurrences or nail regrowth observed during follow-up.
Dermoscopic features of nails in Leprosy patients in a tertiary referral hospital in West Java, Indonesia.
BMC Infect Dis
March 2024
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Article Synopsis
- Leprosy is a chronic infectious disease caused by Mycobacterium leprae, primarily affecting the skin and peripheral nerves, with few studies focusing on its impacts on nails.
- An observational study in West Java, Indonesia, sought to document nail changes in leprosy patients using dermoscopy, revealing that a significant number of patients experienced various dermoscopic nail abnormalities.
- The findings indicated that most changes occurred in males and younger patients, with longitudinal ridges being the most common nail feature observed, alongside other conditions like transverse lines and subungual hemorrhage.
Melanoma-like features in pediatric longitudinal melanonychia: A systematic review and meta-analysis.
Pediatr Dermatol
July 2024
Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Article Synopsis
- Pediatric longitudinal melanonychia (LM) can present atypical features that might raise concerns about subungual melanoma; however, careful clinical examination and dermoscopy often indicate a benign condition, potentially avoiding unnecessary nail biopsy.
- A systematic review of 24 studies with 1391 children identified nevus as the most common diagnosis and highlighted key clinical features and outcomes of pediatric LM, showing that complications like progression were relatively low.
- Despite the prevalence of atypical characteristics, malignant transformation in pediatric LM is rare, indicating the importance of thorough assessment and monitoring rather than immediate invasive procedures.
Looking Beyond the Hutchinson Sign: A Retrospective Study of Clinical Factors Indicating the Presence and Invasiveness of Nail Unit Melanoma in Patients With Longitudinal Melanonychia.
Dermatol Surg
January 2024
Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Background: The data underlying this article are available in the article.Longitudinal melanonychia (LM) presents a challenge because nail unit melanoma (NUM) must be considered as a differential diagnosis. Because nail matrix biopsy may result in nail dystrophy, it is important to distinguish NUM from LM.
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