After an intraperitoneal injection of 100 mumol of methionine to rats, there is rapid oxidation of the methyl group of hepatic 5-methyltetrahydrofolate to formate and CO2. Recovery of the methylfolate level starts 2.5 h after the methionine injection, when the hepatic methionine level and the S-adenosylmethionine/S-adenosylhomocysteine ratio have returned to baseline values. S-Adenosylmethionine concentration is still elevated at this time.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1138405 | PMC |
| http://dx.doi.org/10.1042/bj2580611 | DOI Listing |
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