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Genetic characterization of Italian field strains of Schmallenberg virus based on N and NSs genes. | LitMetric

AI Article Synopsis

  • The Schmallenberg virus (SBV) first appeared in Germany in 2011 and has since spread widely across Europe.
  • This study focuses on the genetic analysis of 15 Italian field strains of SBV, collected in 2012 from regions affected during different outbreak seasons.
  • Results showed that while the viruses are generally stable, there are unique variants of the N and NSs proteins in the Italian strains that haven't been found in other European SBV isolates.

Article Abstract

Following its first identification in Germany in 2011, the Schmallenberg virus (SBV) has rapidly spread to many other European countries. Despite the wide dissemination, the molecular characterization of the circulating strains is limited to German, Belgian, Dutch, and Swiss viruses. To fill this gap, partial genetic characterization of 15 Italian field strains was performed, based on S segment genes. Samples were collected in 2012 in two different regions where outbreaks occurred during distinct epidemic seasons. The comparative sequence analysis demonstrated a high molecular stability of the circulating viruses; nevertheless, we identified several variants of the N and NSs proteins not described in other SBV isolates circulating in Europe.

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Source
http://dx.doi.org/10.1007/s11262-016-1335-9DOI Listing

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