Applying the Airbrakes: Treating Mitochondrial Disease with Hypoxia.

Mol Cell

Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. Electronic address:

Published: April 2016

A paper from Jain et al. (2016) using whole-genome CRISPR knockout libraries in human cells and models of mitochondrial disease suggests chronic hypoxia could be an unexpected treatment for disorders of mitochondrial respiration.

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http://dx.doi.org/10.1016/j.molcel.2016.03.027DOI Listing

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