The next step toward GMP-grade production of engineered immune cells.

Oncoimmunology

Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Hematology, University Medical Center Utrecht, Utrecht, The Netherlands.

Published: February 2016

Removing less potent T cell subsets as well as poorly- or non-engineered cells can optimize effectiveness of engineered T cell therapy against cancer. We have recently described a novel, GMP-ready method for the purification of engineered immune cells that might further boost the clinical success of cancer immunotherapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801490PMC
http://dx.doi.org/10.1080/2162402X.2015.1076608DOI Listing

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