Cerebriform Cutaneous Lesions in Pemphigus Vegetans.

Indian J Dermatol

Department of Dermatology, Father Muller Medical College, Mangalore, Karnataka, India.

Published: April 2016

Pemphigus vegetans is an autoimmune bullous disorder characterized by vegetating lesions commonly over the flexures. A 42-year-old female patient came with pemphigus vegetans presenting with interesting cerebriform morphology of the cutaneous lesions over the flexures. Cerebriform tongue, a morphology with typical pattern of sulci and gyri over dorsum of the tongue is a well-known sign seen in pemphigus vegetans. Interestingly, we noticed the typical sulci and gyri pattern in the skin lesions of pemphigus vegetans over the flexures of the body. This clinical sign can be used as a clue in the diagnosis of pemphigus vegetans. Morphology and physical characteristics are important for the diagnosis of the disease. Clinical signs always give a clue to the probable or possible diagnosis in most of the dermatological conditions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817450PMC
http://dx.doi.org/10.4103/0019-5154.177760DOI Listing

Publication Analysis

Top Keywords

pemphigus vegetans
24
cutaneous lesions
8
lesions pemphigus
8
sulci gyri
8
pemphigus
6
vegetans
6
cerebriform cutaneous
4
lesions
4
vegetans pemphigus
4
vegetans autoimmune
4

Similar Publications

Article Synopsis
  • The study focuses on vulvar acantholytic dyskeratoses, which are rare skin conditions affecting the vulva and perineum, with a goal to improve classification and understanding for gynecologic pathologists.
  • Between 1990 and 2023, 16 cases of vulvar acantholytic dyskeratoses were analyzed, mostly affecting women aged 36 to 79, with many presenting asymptomatic or pruritic lesions predominantly on the labia majora.
  • Histologically, these conditions showed features like acantholysis, with some patients responding to local excision or corticosteroids; however, no clear distinction was found between sporadic and syndromic cases based on
View Article and Find Full Text PDF
Article Synopsis
  • A 70-year-old woman had a single wart-like growth on her leg and painful sores in her mouth.
  • Doctors considered possible conditions like lichen simplex chronicus and chromoblastomycosis before diagnosing her with pemphigus vegetans (PVeg).
  • This case emphasizes the need to include PVeg in diagnoses for unusual skin growths, even when they appear in unexpected areas of the body.
View Article and Find Full Text PDF

Pemphigus vegetans is a rare type of pemphigus characterized by vegetative lesions primarily localized to the intertriginous area. Despite its unique clinical presentation, the underlying pathomechanism remains unclear owing to the rarity of the disease. We report a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!