In the present study, we investigate the impact of stratospheric planetary wave reflection on tropospheric weather over Central Eurasia during the 2013 Sudden Stratospheric Warming (SSW) event. We analyze EP fluxes and Plumb wave activity fluxes to study the two and three dimensional aspects of wave propagation, respectively. The 2013 SSW event is excited by the combined influence of wavenumber 1 (WN1) and wavenumber 2 (WN2) planetary waves, which makes the event an unusual one and seems to have significant impact on tropospheric weather regime. We observe an extraordinary development of a ridge over the Siberian Tundra and the North Pacific during first development stage (last week of December 2012) and later from the North Atlantic in the second development stage (first week of January 2013), and these waves appear to be responsible for the excitation of the WN2 pattern during the SSW. The wave packets propagated upward and were then reflected back down to central Eurasia due to strong negative wind shear in the upper stratospheric polar jet, caused by the SSW event. Waves that propagated downward led to the formation of a deep trough over Eurasia and brought extreme cold weather over Kazakhstan, the Southern part of Russia and the Northwestern part of China during mid-January 2013.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823715 | PMC |
http://dx.doi.org/10.1038/srep24174 | DOI Listing |
Objective: Lennox-Gastaut Syndrome (LGS) is a severe, often treatment-resistant epilepsy syndrome typically diagnosed in early childhood. Many have seizures before diagnosis. Some have periods of seizure freedom before treatment resistance, i.
View Article and Find Full Text PDFPediatr Res
December 2024
Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
Background: Added bovine milk fat globule membrane (bMFGM) or bMFGM components in infant formulas may favor language development essential for cognitive maturation in early life. In this study, the influence of infant feeding type on language skills acquisition was investigated.
Methods: Auditory event-related potentials (ERPs) were performed at ~4-6 (baseline) and 24 months of age in infants receiving: human milk, as a reference group (HM, n = 42) or randomized to standard infant formula (SF, n = 53) or similar formula with added bMFGM (EF, n = 48) through 12 months of age.
Lancet Infect Dis
November 2024
Instituto Butantan, São Paulo, Brazil; Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Background: A single-dose dengue vaccine that protects individuals across a wide age range and regardless of dengue serostatus is an unmet need. We assessed the safety and efficacy of the live, attenuated, tetravalent Butantan-dengue vaccine (Butantan-DV) in adults, adolescents, and children. We previously reported the primary and secondary efficacy and safety endpoints in the initial 2 years of follow-up.
View Article and Find Full Text PDFTransl Breast Cancer Res
September 2023
Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China.
N Engl J Med
February 2024
From Instituto Butantan (E.G.K., M.A.T.C., J.A.M., E.G.P., P.E.B., J.C.V.T., V.I., R.P., D.T.C., J.K., A.R.P., F.C.B.), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (E.G.K.), Departamento de Saúde Coletiva, Faculdade de Ciências Médicas Santa Casa de São Paulo (J.C.M.), and Departamento de Clínica Médica, Faculdade de Medicina, Universidade de São Paulo (J.K.), São Paulo, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus (M.V.G.L.), Centro de Pesquisa em Medicina Tropical de Rôndonia, Porto Velho (D.B.P.), Universidade Federal de Roraima, Boa Vista (A.J.F.), Programa de Pós-graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju (R.Q.G.), Faculdade de Medicina da Universidade Federal do Ceará, Fortaleza (I.C.-B.C.), Hospital Universitário Júlio Müller, Cuiabá (C.J.F.F.), Institute Aggeu Magalhães, Fundação Oswaldo Cruz, Recife (E.T.A.M.), Núcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasília (G.A.S.R.), the Center for Advanced and Innovative Therapies, Universidade Federal de Minas Gerais, Belo Horizonte (M.M.T.), Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro (A.M.S.), Medicina e Saúde Pública de Precisão, Fundação Oswaldo Cruz-Instituto Gonçalo Moniz (IGM/FIOCRUZ), Salvador (A.M.P.B., V.S.B.), Hospital São Lucas da Pontificia Universidade Católica do Rio Grande do Sul, Porto Alegre (F.R.), Faculdade de Medicina da Universidade Federal de Mato Grosso do Sul, Campo Grande (E.E.J.), Faculdade de Medicina de Ribeirão Preto, Universidade of São Paulo, Ribeirão Preto (D.T.C.), and Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto (M.L.N.) - all in Brazil; the School of Public Health, University of Pittsburgh, Pittsburgh (E.T.A.M.); the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (S.S.W.); Merck, Rahway, NJ (A.E.-J., T.S., J.-J.L., S.G.K., B.-A.G.C.); Merck Sharp and Dohme, Munro, Argentina (J.M.); and the Department of Pathology, University of Texas Medical Branch, Galveston (M.L.N.).
Background: Butantan-Dengue Vaccine (Butantan-DV) is an investigational, single-dose, live, attenuated, tetravalent vaccine against dengue disease, but data on its overall efficacy are needed.
Methods: In an ongoing phase 3, double-blind trial in Brazil, we randomly assigned participants to receive Butantan-DV or placebo, with stratification according to age (2 to 6 years, 7 to 17 years, and 18 to 59 years); 5 years of follow-up is planned. The objectives of the trial were to evaluate overall vaccine efficacy against symptomatic, virologically confirmed dengue of any serotype occurring more than 28 days after vaccination (the primary efficacy end point), regardless of serostatus at baseline, and to describe safety up to day 21 (the primary safety end point).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!