BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting this potentially deadly virus. The study also serves as a platform for exploring the basic biology of virion assembly and infectious entry.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289593 | PMC |
| http://dx.doi.org/10.1016/j.str.2016.03.011 | DOI Listing |
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