Objective: To assess the inter-rater reliability of two raters for the mean and single maximal value of three vaginal maximum voluntary contractions (MVCs) using the Peritron™ perineometer for study participants in the first and second trimesters of pregnancy.
Participants: Thirty-six low-risk pregnant women.
Methods: The assessments were done by two different examiners with an interval of 2 to 7 days. For statistical analysis, the concordance correlation coefficient (CCC) and Bland-Altman limits of agreement were used.
Results: For the overall sample, good reliability of 0.80 was found analyzing the mean of three MVCs and for the single maximal value (CCC = 0.79). Good reliability was found for the mean of three MVCs (0.81 and 0.78) for the first and second trimesters, respectively. Good reliability of 0.89 was found in the first trimester and a moderate reliability of 0.70 for the second trimester when analyzing the single maximal value of three MVCs.
Conclusion: Good inter-rater reliability was found for the overall sample and first trimester of pregnancy for both mean values and single maximal values of the three MVCs. A good and moderate reliability was respectively found in the second trimester in analyzing the mean and single maximum values of three MVCs.
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http://dx.doi.org/10.3109/09593985.2015.1129654 | DOI Listing |
Clin Pharmacol Drug Dev
January 2025
Taiho Pharmaceutical Co., Ltd., Tokyo, Japan.
Pizuglanstat is a novel hematopoietic prostaglandin D synthase inhibitor and investigational treatment for Duchenne muscular dystrophy. This Phase 1 mass balance study aimed to characterize the absorption, metabolism, and excretion of carbon-14 (C)-labeled pizuglanstat in healthy adults (ClinicalTrials.gov, NCT04825431).
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, United States.
Objectives: Preventing malnutrition during chemoradiation (CRT) for head and neck cancer is critical maximizing quality of life (QOL). We sought to assess patient-reported QOL outcomes after integrating exclusive liquid meal replacement with Soylent, a novel meal replacement agent, in patients with head and neck cancer undergoing CRT.
Methods: Patients undergoing definitive or adjuvant concurrent CRT for locally advanced head and neck cancer enrolled on our single-institution, prospective phase II protocol evaluating nutritional replacement with Soylent.
J Hip Preserv Surg
December 2024
Department of Orthopaedic Surgery, Stanford University School of Medicine, 453 Quarry Road, Palo Alto, CA 94304, USA.
Adverse mental health status has been linked to less successful surgical outcomes across several orthopaedic subspecialties. Mental health represents a modifiable risk factor that can be optimized preoperatively to maximize outcomes for hip preservation surgery. This study examines the relationship between preoperative mental health status and preoperative and postoperative outcomes for adolescent and adult patients undergoing hip preservation surgery.
View Article and Find Full Text PDFInt J Sports Physiol Perform
January 2025
Faculty of Education Sciences and Physiology, University of Latvia, Riga, Latvia.
Purpose: Speed is a crucial physical characteristic where each lower-limb ankle plantar-flexor (PF) muscle needs to generate significant force; however, there is limited evidence about the relationship between single-limb isometric, and reactive strength forms, and linear sprint. The aim of this study was to determine the impact of the maximal unilateral isometric strength of the ankle PF muscle and reactive strength on sprint acceleration performance.
Material And Methods: Thirty-two male floorball players (mean [SD] age 20.
Exp Physiol
January 2025
Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Perth, Australia.
Blood flow restriction (BFR) combined with low work rate exercise can enhance muscular and cardiovascular fitness. However, whether neural mechanisms mediate these enhancements remains unknown. This study examined changes in corticospinal excitability and motor cortical inhibition following arm cycle ergometry with and without BFR.
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