Envenoming by the Australian red-bellied black snake (Pseudechis porphyriacus) causes non-specific systemic symptoms, anticoagulant coagulopathy, myotoxicity and local effects. Current management for systemic envenoming includes administration of one vial of tiger snake antivenom within 6 h of the bite to prevent myotoxicity. We present a case of severe rhabdomyolysis in a 16 year old male which developed despite early administration of one vial of tiger snake antivenom. Free venom was detected after the administration of antivenom concurrent with rapidly decreasing antivenom concentrations. The case suggests that insufficient antivenom was administered and the use of larger doses of antivenom need to be explored for red-bellied black snake envenoming.
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http://dx.doi.org/10.1016/j.toxicon.2016.03.016 | DOI Listing |
Clin Toxicol (Phila)
January 2025
Clinical Toxicology Research Group, University of Newcastle, Newcastle, Australia.
Objective: Early antivenom administration is essential for effective treatment. We investigated the delays in antivenom administration.
Methods: We reviewed snakebites from the Australian Snakebite Project (2006-2021) given antivenom, presenting to hospital within 12 h.
Animals (Basel)
November 2024
Department of General Psychology, University of Padova, Via Venezia 8, 35131 Padova, Italy.
Clin Toxicol (Phila)
June 2024
Department of Clinical Toxicology, Newcastle, Australia.
Clin Toxicol (Phila)
May 2024
Clinical Toxicology Research Group, University of Newcastle, Newcastle, NSW, Australia.
Introduction: Myotoxicity is an important toxidrome that can occur with envenoming from multiple Australian snake types. Early antivenom administration is an important strategy to reduce the incidence and severity of myotoxicity. The current gold standard biomarker, serum creatine kinase activity, does not rise early enough to facilitate early antivenom administration.
View Article and Find Full Text PDFParasitol Res
January 2024
Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, New South Wales, 2006, Australia.
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