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Thyroid eye disease and ocular myasthenia gravis.
Curr Opin Neurol
February 2025
Edward S. Harkness Eye Institute, Columbia University, New York, New York, USA.
Purpose Of Review: An overview of two ocular diseases, which significantly impact quality of life: thyroid eye disease (TED) and ocular myasthenia gravis (OMG). Additionally, we describe the clinical challenge when they occur simultaneously. We will describe the pathophysiology of both conditions, the currently available diagnostic tools, and the therapies available.
View Article and Find Full Text PDFAn extremely rare case of thymic squamous cell carcinoma complicated with B3 thymoma and myasthenia gravis: a case report.
Surg Case Rep
September 2024
Department of Pathology, Japanese Red Cross Akita Hospital, 222-1 Nawashirosawa, Saruta Kamikitate, Akita, 010-1495, Japan.
Article Synopsis
- A 65-year-old female with myasthenia gravis underwent surgery for a tumor suspected to be a thymoma following CT scans that indicated an anterior mediastinal mass.
- During surgery, it was found that her tumor was a combination of a B3 thymoma and thymic squamous cell carcinoma, which is a rare occurrence.
- Post-surgery, she received adjuvant radiotherapy and is currently being monitored with no signs of cancer recurrence noted in follow-up scans.*
Dropped Head Syndrome: The Importance of Neurophysiology in Distinguishing Myasthenia Gravis from Parkinson's Disease.
Biomedicines
August 2024
Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH 45219, USA.
Article Synopsis
- Dropped head syndrome (DHS) involves severe neck flexion due to neck muscle tone imbalance, often linked to neuromuscular conditions like myasthenia gravis (MG), while Parkinson's disease (PD) may present with a similar issue called antecollis without muscle weakness.
- A case study of a 71-year-old man showed symptoms of neck flexion and Parkinsonism, including rigidity and reduced arm swing, but also revealed significant neck muscle weakness and confirmed MG with specific tests.
- Successful treatment involved medications for both MG (pyridostigmine and plasma exchange) and PD (carbidopa/levodopa), emphasizing the importance of detailed clinical evaluations to address the complex interplay between these conditions
A perplexing case report of concomitant multiple sclerosis and myasthenia gravis.
Ann Med Surg (Lond)
July 2024
Departments of Internal Medicine.
Introduction And Importance: The co-occurrence of multiple sclerosis (MS) and myasthenia gravis (MG) within the Middle East and North African Region (MENA) has been scarcely reported in current literature. This rare case report explores the pathophysiological mechanisms and potential avenues of treatment modalities. Such insights can potentially facilitate the development of more efficacious and targeted treatment modalities and perhaps pave the way for disease prevention.
View Article and Find Full Text PDFA Contemporaneous Onset of Eosinophilic Granulomatosis with Polyangiitis and Myasthenia Gravis: A Case Report.
Intern Med
July 2024
Center for Immunology and Allergy, Shonan Kamakura General Hospital, Japan.
Article Synopsis
- Autoimmune neuromuscular disorders like myasthenia gravis (MG) are rare in patients with eosinophilic granulomatosis with polyangiitis (EGPA).
- Two previous cases of MG alongside EGPA were reported, but in those instances, EGPA occurred years after starting MG treatment.
- A 75-year-old man is described who had both EGPA and MG simultaneously, and he was successfully treated with immunosuppressive therapy; it's important to differentiate symptoms of each condition in patients with eosinophilia.
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