Dietary exclusion of gluten-containing products has become increasingly popular in the general population, and currently ∼30% of people in the United States are limiting gluten ingestion. Although celiac disease (CD), wheat allergy (WA), and nonceliac gluten sensitivity (NCGS) constitute a spectrum of gluten-related disorders that require exclusion of gluten from the diet, together these account for a relatively small percentage of those following a gluten-free diet, and the vast majority has no medical necessity for doing so. Differentiating between CD, WA, and NCGS has important prognostic and therapeutic implications. Because of the protean manifestations of gluten-related disorders, it is not possible to differentiate between them on clinical grounds alone. This clinical report will compare and contrast the manifestations of gluten-related disorders, emphasize the importance of differentiating between these conditions, discuss initial and subsequent tests needed to confirm the diagnosis, and provide recommendations on treatment and follow-up for each condition.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MPG.0000000000001216 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Serum metabolomics and lipoproteomics discriminate celiac disease and non-celiac gluten sensitivity patients.
Clin Nutr
December 2024
Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy. Electronic address:
Background&aims: Celiac disease (CD) and potential CD (pCD) are immune-mediated disorders triggered by the ingestion of gluten. In non-celiac gluten sensitivity (NCGS) neither allergic nor autoimmune mechanisms are involved. Relationships between NCGS and CD need to be further investigated.
View Article and Find Full Text PDFViral infections in celiac disease: what should be considered for better management.
Clin Exp Med
December 2024
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Following a gluten-free diet (GFD) is known as the main effective therapy available for celiac disease (CD) patients, which in some cases is not enough to heal all patients presentations completely. Accordingly, emerging researchers have focused on finding novel therapeutic/preventive strategies for this disorder. Moreover, previous studies have shown that celiac patients, especially untreated subjects, are at increased risk of developing viral and bacterial infections, which can become a challenge for the clinician.
View Article and Find Full Text PDFOptimization of Functional Gluten-Free Cake Formulation Using Rice Flour, Coconut Flour, and Xanthan Gum via D-Optimal Mixture Design.
Food Sci Nutr
December 2024
Department of Food Science and Technology, Science and Research Branch Islamic Azad University Tehran Iran.
Article Synopsis
- Prolamins found in wheat, barley, and rye are linked to health issues like celiac disease and wheat allergies, pushing the need for gluten-free alternatives like rice flour, though its products are not as high-tech.
- Adding low-fat desiccated coconut flour and xanthan gum to rice flour significantly improves the quality and properties of gluten-free cakes, impacting viscosity, moisture, and texture.
- The study successfully optimized a gluten-free cake recipe, achieving improved sensory qualities (taste, texture, etc.) through careful ratios of rice flour, coconut flour, and xanthan gum, validated by strong statistical models.
FODMAP Diet in Celiac Disease and Gluten-Related Disorders.
Nutrients
December 2024
Digestive Endoscopy, ARNAS G. Brotzu, 09121 Cagliari, Italy.
Background: Individuals with celiac disease (CD) often report the persistence of gastrointestinal symptoms despite adherence to a gluten-free diet (GFD). A diet rich in fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) could cause symptoms in CD on a GFD, and conversely a low-FODMAP diet could positively influence the therapeutic management of CD and non-celiac gluten sensitivity (NCGS). The aim of this review was to explore the hypothetical impact of the FODMAD diet and the low-FODMAP diet (LFD) in CD and gluten-related disorders.
View Article and Find Full Text PDFA Call to Action: Unraveling the Nuance of Adapted Eating Behaviors in Individuals with GI Conditions.
Clin Gastroenterol Hepatol
December 2024
The Rome Foundation Research Institute, Chapel Hill, NC.
The primary aim of this expert narrative review is to unravel the complexities of feeding and eating disorders in the gastroenterology practice setting. We aim to critically assess current assessment screening tools for eating and feeding disorders to gain a comprehensive understanding of how these tools may be misconstrued in the context of gastrointestinal (GI) conditions. Additionally, our objective is to highlight the potential for over-pathologizing and under-pathologizing eating behavior in this patient population.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!