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Effect of head size, head material, and radiation dose on the repeatability of CT-RSA measurements of femoral head penetration.
J Mech Behav Biomed Mater
January 2025
Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Department of Medical Biophysics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:
Background: The risk of early revision of total hip arthroplasty (THA) for polyethylene wear is now low, but there remains a need to perform wear measurements in patients for clinical surveillance. The gold standard of wear measurements has been radiostereometric analysis (RSA), which has limited availability. The use of computed tomography (CT) to perform THA wear measurement was described a decade ago and found to have acceptable accuracy and precision, but high radiation dose was a concern.
View Article and Find Full Text PDFA Nomogram Built on Clinical Factors and CT Attenuation Scores for Predicting Treatment Response of Acute Myeloid Leukemia Patients.
Biomedicines
January 2025
Clinical Research Center, Jiangnan University Medical Center, 68 Zhongshan Road, Wuxi 214002, China.
Acute myeloid leukemia (AML) is an aggressive cancer with variable treatment responses. While clinical factors such as age and genetic mutations contribute to prognosis, recent studies suggest that CT attenuation scores may also predict treatment outcomes. This study aims to develop a nomogram combining clinical and CT-based factors to predict treatment response and guide personalized therapy for AML patients.
View Article and Find Full Text PDFClinical application of third-generation dual-source CT-based dynamic imaging reconstruction for pulmonary embolism imaging.
J Cardiothorac Surg
January 2025
Department of Thyroid Breast Cardiothoracic & Vascular Surgery, Beibei District Hospital of Traditional Chinese Medicine, No. 380 Jiangjun Road, Beibei District, Chongqing, 400700, China.
Background: To evaluate the clinical diagnostic value of third-generation dual-source CT for pulmonary embolism, focusing on the optimization of dual-source CT scanning with dynamic reconstruction in acute pulmonary embolism (PE) and various imaging manifestations.
Methods: Eighty-two patients with pulmonary embolism were enrolled and randomly divided into standard CT angiography (SCTA) and dynamic CT angiography (DCTA). DCTA patients were divided into dynamic CT angiography arterial phase (DCTAa), time phase Angiography reconstruction (TMIP-CTA), and 4D noise reduction TMIP-CTA according to the image reconstruction.
CT-based radiomics predicts HRD score and HRD status in patients with ovarian cancer.
Front Oncol
January 2025
Department of Gynecology, Liaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Introduction: This study predicted HRD score and status based on intra- and peritumoral radiomics in patients with ovarian cancer (OC) for better guiding the use of PARPi in clinical.
Methods: A total of 106 and 95 patients with OC were included between January 2022 and November 2023 for predicting HRD score and status, respectively. Radiomics features were extracted and quantitatively analyzed from intra- and peri-tumor regions in the CT image.
Preoperative CT-based radiomics nomogram to predict the micropapillary pattern in lung adenocarcinoma of size 2 cm or less.
Front Oncol
January 2025
Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Purpose: To develop and validate a radiomics nomogram model for predicting the micropapillary pattern (MPP) in lung adenocarcinoma (LUAD) tumors of ≤2 cm in size.
Methods: In this study, 300 LUAD patients from our institution were randomly divided into the training cohort (n = 210) and an internal validation cohort (n = 90) at a ratio of 7:3, besides, we selected 65 patients from another hospital as the external validation cohort. The region of interest of the tumor was delineated on the computed tomography (CT) images, and radiomics features were extracted.
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