Introduction: Current tools and methods in architectural design do not allow predicting and evaluating how people will use designed environments before their actual realization.
Objective: To investigate how computational simulation can help in evaluating design proposals as far as their use by people is concerned.
Methods: Simulation of a medicine distribution procedure in a general hospital facility, while accounting for serendipitous social interactions made possible by the presence of different users in the same space, at the same time.
Discussion: The simulation shows how use patterns are influenced by the social and physical context in which actors are situated, and demonstrates the significance of the proposed method of evaluating hospital designs before construction. The system allows simulating use patterns with different degrees of complexity, and enables architects to ask new types of questions related to the interactions between people and physical settings.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.4415/ANN_16_01_07 | DOI Listing |
Acc Chem Res
January 2025
Organisch-Chemisches Institut, Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
ConspectusSkeletal editing, which involves adding, deleting, or substituting single or multiple atoms within ring systems, has emerged as a transformative approach in modern synthetic chemistry. This innovative strategy addresses the ever-present demand for developing new drugs and advanced materials by enabling precise modifications of molecular frameworks without disrupting essential functional complexities. Ideally performed at late stages of synthesis, skeletal editing minimizes the need for the cost- and labor-intensive processes often associated with synthesis, thus accelerating the discovery and optimization of complex molecular architectures.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Biology Department, University of Massachusetts Amherst, Amherst, MA, USA.
Background: High-throughput behavioral analysis is important for drug discovery, toxicological studies, and the modeling of neurological disorders such as autism and epilepsy. Zebrafish embryos and larvae are ideal for such applications because they are spawned in large clutches, develop rapidly, feature a relatively simple nervous system, and have orthologs to many human disease genes. However, existing software for video-based behavioral analysis can be incompatible with recordings that contain dynamic backgrounds or foreign objects, lack support for multiwell formats, require expensive hardware, and/or demand considerable programming expertise.
View Article and Find Full Text PDFInternet of Things (IoT) is one of the most important emerging technologies that supports Metaverse integrating process, by enabling smooth data transfer among physical and virtual domains. Integrating sensor devices, wearables, and smart gadgets into Metaverse environment enables IoT to deepen interactions and enhance immersion, both crucial for a completely integrated, data-driven Metaverse. Nevertheless, because IoT devices are often built with minimal hardware and are connected to the Internet, they are highly susceptible to different types of cyberattacks, presenting a significant security problem for maintaining a secure infrastructure.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Computer Science, Xi'an University of Architecture and Technology, Xi'an, 710055, Shaanxi Province, China.
The attention mechanism has significantly progressed in various point cloud tasks. Benefiting from its significant competence in capturing long-range dependencies, research in point cloud completion has achieved promising results. However, the typically disordered point cloud data features complicated non-Euclidean geometric structures and exhibits unpredictable behavior.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Chemical and Environmental Engineering, Yale University, New Haven, CT, USA.
Discharge of wastewater containing nitrate (NO) disrupts aquatic ecosystems even at low concentrations. However, selective and rapid reduction of NO at low concentration to dinitrogen (N) is technically challenging. Here, we present an electrified membrane (EM) loaded with Sn pair-atom catalysts for highly efficient NO reduction to N in a single-pass electrofiltration.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!