Patients with critical limb ischaemia, without possibility for vascular surgery reconstruction, are a high selected population with a wide scale occurrence of co-morbidity and mortality. We outline the use of intermittent pneumatic compression (IPC) to these patients. Impact on both wound healing and cost-effectiveness concerning IPC use are recently shown. The overriding purpose of IPC use is to decrease the frequency of major and to lower the extent of ischaemic rest pain. IPC equipment is currently available around the country, but is not often used on the indication critical limb ischaemia.
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Neurology
February 2025
Division of Clinical and Metabolic Genetics, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
Pathogenic variants in cause congenital muscular dystrophy through hypoglycosylation of alpha-dystroglycan (OMIM #615350). The established phenotypic spectrum of GMPPB-related disorders includes recurrent rhabdomyolysis, limb-girdle muscular dystrophy, neuromuscular transmission abnormalities, and congenital muscular dystrophy with variable brain and eye anomalies. We report a 9-month-old male infant with congenital muscular dystrophy, infantile spasms, and compound heterozygous pathogenic variants (c.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, Merit Health Wesley, Hattiesburg, USA.
Anterior cord syndrome is a rare yet critical neurological condition that poses significant challenges in clinical management. We present the case of a 71-year-old male with a medical history of hypertension, uncontrolled type II diabetes mellitus, hypothyroidism, and end-stage renal disease requiring dialysis who presented to the emergency department with complaints of chills, back pain, abdominal pain, and vomiting episodes. Based on the severity of the patient's illness, it was decided that inpatient admission would be best.
View Article and Find Full Text PDFProsthet Orthot Int
January 2025
School of Physical Education and Physiotherapy, Federal University of Uberlândia (UFU), Minas Gerais, Brazil.
Background: Preferred walking speed (PWS), maximal walking speed (MWS), and walking speed reserve (WSR)-the difference between MWS and PWS-can be easily obtained from the 10-m walk test (10MWT) to assess walking ability and function. However, their test-retest reliability has not been determined in persons with unilateral lower-limb amputation (LLA).
Objectives: To determine the reliability of the PWS, MWS, and WSR obtained from the 10MWT in persons with LLA.
BMJ Open
December 2024
Department of Vascular Surgery, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
Introduction: Foot ulcers are one of the most serious complications of diabetes, leading to significant risks on amputation and mortality. Peripheral arterial disease (PAD) is an important factor for the development and the outcome of diabetic foot ulcers (DFU). Although prompt and accurate detection of PAD is critical to reduce complications, its diagnosis can be challenging with currently used bedside tests (such as ankle-brachial index and toe pressure) due to medial arterial calcification.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
January 2025
From the Israel Defense Forces, Medical Corps, Kiryat Ono (Shapira, and Epstein), the Faculty of Medicine, The Hebrew University, Jerusalem (Shapira), the Sheba Medical Center, Tel Hashomer, Ramat Gan (Shapira), the Israel National Center for Trauma and Emergency Medicine Research, Gertner Institute of Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan (Goldman, Givon, and Katorza), the Arrow Program for Medical Research Education, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan (Katorza), the Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv (Katorza, Dudkiewicz, and Prat), the Rehabilitation Division, Sheba Medical Center, Tel Hashomer, Ramat Gan (Dudkiewicz), the Critical Care Division, Rambam Health Care Campus, Haifa (Epstein), the Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa (Epstein), and the Department of Orthopaedic Surgery, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel (Prat).
Background: In modern conflicts, extremities are mainly affected, with limb amputations required for approximately 5% of severely injured combatants and 7% of those with serious limb injuries. Amputations are some of the most challenging injuries endured by survivors, significantly affecting the patients and the healthcare system. This study aims to describe the rates, characteristics, and risk factors of limb amputations in patients with serious extremity trauma during the 2023 conflict in Israel.
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