Antigen cross presentation is important for effective immune responses to tumors and viral infections. Dendritic cells are professional antigen presenting cells and are unique in their ability to cross-present exogenous antigens on MHC class I molecules and activate antigen specific cytotoxic T cells. This protocol describes antigen cross presentation by dendritic cells (DCs) (bone marrow derived DCs and splenic DCs) in an and in an assay system using soluble ovalbumin protein.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809020 | PMC |
| http://dx.doi.org/10.21769/bioprotoc.305 | DOI Listing |
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