Transepithelial Photorefractive Keratectomy for Hyperopia: A 12-Month Bicentral Study.

Purpose: To investigate the safety, efficacy, and stability of transepithelial photorefractive keratectomy (PRK) for hyperopia.

Methods: This interventional case series study at two sites included 55 eyes (31 patients) with hyperopia (0.50 to 6.00 diopters [D]), with or without astigmatism (0.00 to -3.00 D), that underwent one-step transepithelial PRK with a Amaris 500-Hz excimer laser (SCHWIND eye-tech-solutions, Kleinostheim, Germany). A 12-month follow-up was conducted. Preoperative and successive postoperative visual acuity, manifest refraction, haze, and other complication data were analyzed.

Results: The preoperative mean spherical equivalent of 2.56 ± 1.90 D improved to emmetropia (-0.08 ± 0.14 D) by 6 months, with subsequent slight mean regression of 0.024 D (range: -0.75 to 0.50) until month 12. Of the treated eyes, 75% and 76.2% were within the target refraction of ±0.50 D at 6 and 12 months postoperatively, respectively. The final mean cylindric refraction was comparable to the preoperative value (-0.94 ± 0.12 to -0.71 ± 0.12 D, P = .17); however, it was induced in 23% of eyes. The preoperative mean uncorrected distance visual acuity logMAR of 0.54 ± 0.05 significantly improved to 0.15 ± 0.03 by month 12 (P < .0001), and 64.2% of the treated eyes gained an uncorrected distance visual acuity of 20/25 or better. Ten eyes (23.8%) lost one line of preoperative corrected distance visual acuity (CDVA). No eye lost two or more lines of preoperative CDVA. Four eyes with a 3+ degree of haze were observed by the final visit. No other notable complications occurred. The low hyperopic eyes exhibited better overall results compared to the moderate hyperopic group.

Conclusions: One-step transepithelial PRK with the Amaris 500-Hz excimer laser provided reasonable outcomes for the correction of hyperopia with or without mild to moderate astigmatism.