Objective: To establish reference range for uterine artery (UtA) Doppler pulsatility index (PI) using transvaginal ultrasound at 20-24w6d of gestation in a Brazilian population.
Material And Methods: A retrospective cross-sectional study in 847 low-risk pregnant women undergoing routine second trimester ultrasound examination was conducted from February 2012 through March 2015. The mean UtA PI was calculated using color Doppler ultrasound with UtA gated at the level of the internal os. Mean±standard deviation and ranges for UtA Doppler PI in relation to gestational age (GA) are reported. Polynomial regression was used to obtain the best fit using mean UtA Doppler PI and GA (weeks) with adjustments performed using determination coefficient (R(2)). The 5(th), 50(th), and 95(th) percentiles for the mean UtA Doppler PI in relation to GA were determined.
Results: The mean UtA Doppler PI ranged from 1.14 at 20 weeks to 0.95 at 24 weeks of gestation. The best-fit curve of mean UtA Doppler PI as a function of GA was a first-degree polynomial regression: mean UtA Doppler PI=1.900-0.038×GA (R(2)=0.01).
Conclusion: In summary, when the mean UtA PI Doppler values were measured by transvaginal ultrasound at 20-24w6d of gestation, decrease in UtA Doppler PI values with advancing GA was observed. Reference range for the mean UtA Doppler PI at 20-24w6d of gestation using the transvaginal ultrasound in a low-risk Brazilian population was established. We believe that this reference range may be of clinical value in daily obstetric practice.
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http://dx.doi.org/10.5152/jtgga.2016.16192 | DOI Listing |
Arch Gynecol Obstet
January 2025
Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Purpose: To quantify the separation between maternal blood cell-free (cf)DNA markers in preeclampsia and unaffected pregnancies and compare with existing markers. This approach has not been used in previous studies.
Methods: Comprehensive systematic literature search of PubMed to identify studies measuring total cfDNA, fetal cf(f)DNA or the fetal fraction (FF) in pregnant women.
J Ethnopharmacol
January 2025
Department of Ilmul Saidla (Pharmacy), National Institute of Unani Medicine, Ministry of Ayush, GOI, Bengaluru, India. Electronic address:
Ethnopharmacology Relevance: Incorporating ancient wisdom from Unani Medicine, this study delves into the therapeutic efficacy of Juniperus communis L. in primary dysmenorrhea. By seamlessly merging traditional knowledge with modern scientific evaluation, this research illuminates Juniperus communis L.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
January 2025
Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Objectives: To examine the relationship of ophthalmic artery (OA) Doppler indices with uterine artery (UtA) Doppler indices, selected maternal hemodynamic parameters and gestational age, and to evaluate the intraobserver reproducibility of OA Doppler indices.
Methods: This was a prospective cohort study of women recruited between 11 + 0 and 23 + 6 weeks' gestation using a stratified and random sampling approach to ensure adequate distribution across the gestational-age range. OA pulsatility index (PI), first peak systolic velocity (PSV1), second peak systolic velocity (PSV2) and peak systolic velocity ratio (PSV ratio), calculated as PSV2/PSV1, were measured twice in each eye by the same observer.
PLoS One
January 2025
Department of Radiology, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Background: Previous studies have shown that higher uterine artery pulsatility index (UtA-PI) values in early pregnancy have predictive value for the risk of preeclampsia (PE). However, the sensitivity and specificity of this marker remain controversial. This study aims to explore further the association between UtA-PI in early pregnancy and the incidence of preeclampsia.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
January 2025
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.
Objective: Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long-term cardiovascular disease that occurs earlier in life. This study aimed to assess maternal hemodynamic and vascular parameters at 35-37 weeks' gestation, to understand the alterations that may occur in association with increased maternal BMI and gestational weight gain, and to evaluate obesity-related pregnancy outcomes.
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