The results of induction chemotherapy were analysed in cases of advanced ovarian carcinoma grade III (FIGO) during second-look operation. In 108 cases after the first operation with varying degree of radical removal of the tumour chemotherapy was given by the PAC schedule (cisplatin, adriablastin, cyclophosphamide) achieving in 90 cases 9 treatment courses. The results were evaluated using WHO clinical criteria. The best therapeutic results were noted in patients after radical operations or with aggressive cytoreduction of tumour mass. The clinical assessment of chemotherapy was corrected during the second-look operation which led to reduction of the percent of cured cases.
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