In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.
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http://dx.doi.org/10.1016/j.mimet.2016.03.016 | DOI Listing |
Dalton Trans
January 2025
Center for Research, Innovation, Development, and Applications (CRIDA), Jaiotec Labs (OPC) Private Limited, Amaravati, AP, 522503, India.
The existing demand for the development of innovative multimodal imaging nanomaterial probes for biomedical applications stems from their unique combination of dual response modalities, , photoluminescence (PL) and magnetic resonance imaging (MRI). In this study, for the first time, neodymium (Nd) and dysprosium (Dy) rare earth (RE) metal ions were co-doped into a hydroxyapatite (HAp) crystal lattice using a simple microwave-assisted synthesis technique to incorporate the essential properties of both the lanthanides in HAp. Theoretical as well as experimental studies were performed on novel Nd:Dy:HAp nanoparticles (NPs) to understand their photoluminescence and magnetic behaviour.
View Article and Find Full Text PDFF1000Res
January 2025
Department of Orthopaedics, Leiden University Medical Center, Leiden, Albinusdreef 2, 2333 ZA, The Netherlands.
Background: Prosthetic joint infection is a serious complication that can arise after total joint replacement surgery. When bacteria colonise an orthopaedic implant, they form biofilms that protect them from their environment, making them difficult to remove. Treatment is further complicated by a global rise of antimicrobial resistance.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
January 2025
School of Materials Science and Engineering, University of Jinan, Jinan, 250022, China. Electronic address:
Silicon nitride (Si₃N₄) ceramics exhibit excellent mechanical properties and biocompatibility, making them highly suitable for biomedical applications, particularly in implants. In this study, the mechanical properties and bioactivity of Si₃N₄ ceramics with varying amounts of Y₂O₃-Al₂O₃-SiO₂ sintering aids were investigated. Increasing the sintering additive content from 4 wt% to 8 wt% substantially improved the bulk density of the ceramics, leading to notable enhancements in mechanical properties.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Department of Dental Medicine and Nursing, Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Following implantation, infections, inflammatory reactions, corrosion, mismatches in the elastic modulus, stress shielding and excessive wear are the most frequent reasons for orthopedic implant failure. Natural polymer-based coatings showed especially good results in achieving better cell attachment, growth and tissue-implant integration, and it was found that the inclusions of nanosized fillers in the coating structure improves biomineralization and consequently implant osseointegration, as the nanoparticles represent calcium phosphate nucleation centers and lead to the deposition of highly organized hydroxyapatite crystallites on the implant surface. In this study, magnetic nanoparticles synthesized by the co-precipitation method were used for the preparation of cellulose acetate composite coatings through the phase-inversion method.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Institute of Physical Chemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl.11, 1113 Sofia, Bulgaria.
Calcium phosphates are often used for biomedical applications. Hydroxyapatite, for example, has a wide range of applications because it mimics the mineral component of natural bone. Widespread interest in the catalytic properties of ceria is due to its use in automotive catalytic converters.
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