Conservation biologists now realize that parasites of endangered hosts should be conserved for their own sake and as part of their host's natural environment. But parasites should also be conserved because parasitic exposure might be crucial to the host's development of a fully functional immune system and hence to the survival of the host.
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Postpartum Hemorrhage in Humanitarian Settings: Implementation Insights from Using Heat-Stable Carbetocin and Tranexamic Acid.
Int J MCH AIDS
September 2024
United Nations Population Fund, Humanitarian Response Division, Switzerland.
Article Synopsis
- Maternal mortality due to postpartum hemorrhage (PPH) is a significant issue in low-resource settings, and this study examines healthcare providers' perspectives on the effectiveness and challenges of using heat-stable carbetocin (HSC) and tranexamic acid (TXA) for prevention and treatment of PPH.
- The research involved semi-structured interviews and focus group discussions with 64 healthcare workers in South Sudan and Uganda, focusing on a PPH intervention package that included training, readiness kits, and a community support platform.
- Results indicated providers view HSC favorably for preventing bleeding and recognize TXA as effective but noted limited experience with it; challenges included medication confusion and record-keeping issues, while
CRISPR/Cas9 improves targeted knock-in efficiency in .
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Research Institute, Gekkeikan Sake Co., Ltd., 101 Shimotoba-koyanagi-cho, Fushimi-ku, Kyoto, 612-8385, Japan.
is an important fungus in food and industrial enzyme production. In , targeted knock-in transformation is primarily limited to homologous recombination (HR)-based systems, in which non-homologous end-joining (NHEJ)-disruptant hosts are required. However, preparation of hosts and transformation templates for such systems is laborious, in addition to other disadvantages.
View Article and Find Full Text PDFMolecular Engines, Therapeutic Targets, and Challenges in Pediatric Brain Tumors: A Special Emphasis on Hydrogen Sulfide and RNA-Based Nano-Delivery.
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Molecular Genetics Research Team (MGRT), Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11835, Egypt.
Pediatric primary brain tumors represent a real challenge in the oncology arena. Besides the psychosocial burden, brain tumors are considered one of the most difficult-to-treat malignancies due to their sophisticated cellular and molecular pathophysiology. Notwithstanding the advances in research and the substantial efforts to develop a suitable therapy, a full understanding of the molecular pathways involved in primary brain tumors is still demanded.
View Article and Find Full Text PDFWildlife must be protected from crime and trade for the sake of public and planetary health.
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Global Initiative to End Wildlife Crime, hosted by ADM Capital Foundation, Central, Hong Kong SAR, China.
COVID-19 most likely had its origins in wildlife, and hundreds of thousands of new viruses could spill over from wildlife to humans. We are struggling to combat climate change, and we are staring down the loss of a million species. It's time to change course.
View Article and Find Full Text PDFManagement of Pediatric Kidney Transplant Patients During the COVID-19 Pandemic: Guidance From the Canadian Society of Transplantation Pediatric Group.
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Division of Nephrology, Alberta Children's Hospital, Calgary, Canada.
Purpose Of The Program: To provide guidance on the management of pediatric kidney transplant patients during the COVID-19 pandemic.
Sources Of Information: Program-specific documents, preexisting, and related to COVID-19; documents from provincial, national, and international kidney transplant societies/agencies and organ procurement agencies; national and international webinars, including webinars that we hosted for input and feedback; with additional information from formal and informal review of published academic literature.
Methods: Challenges in the care of pediatric kidney transplant patients during the COVID-19 pandemic were highlighted within the Canadian Society of Transplantation (CST) Pediatric Group.
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