Nitric oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that the NO dosage and biological response can be tuned this approach to suit the requirements of particular applications.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786954PMC
http://dx.doi.org/10.1039/c5ra24023aDOI Listing

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