Results of the multicentric investigation of therapeutic efficacy of glycvidon were presented in this paper. The investigation was performed in 15 centres and comprised 768 patients with type 2 diabetes mellitus. A considerable improvement in metabolic regulation was attained which led to the reduction in glycemia level on an empty stomach and after the meal, to the reduction or elimination of glycosuria and to the significant decrease in glycolized hemoglobin. A parallel improvement in serum lipid levels was also registered. Tolerance of glycvidon was good and hypoglycemic incidents were very rare and as a rule of mild degree.

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