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The Trends, Clinicopathological Features, and Treatment Outcomes of Patients with Prostate Cancer in Lokoja, Nigeria.
J West Afr Coll Surg
August 2024
Division of Urology, Department of Surgery, College of Health Sciences, University of Abuja, Abuja, Nigeria.
Background: Prostate cancer (PCa) was the most common noncutaneous cancer among Nigerian men in 2020. Despite this high incidence, documented rates may be an underestimation.
Objectives: This study aimed to determine the hospital incidence rate, trends, and characterise the clinicopathologic features, and treatment outcomes of patients with PCa in our institution.
Diversity-Related, Student-Led National Medical Organizations: Leadership Opportunities for Learners.
MedEdPORTAL
December 2024
Dean, Universidad Central Del Caribe, School of Medicine; Executive Director, Latino Medical Student Association.
Introduction: In light of the lack of diversity in academic medicine leadership, diversity-related, student-led national medical organizations (NMOs) provide a space for solace and reprieve among common peers while providing an opportunity to develop leadership competencies in a supportive environment. Despite the impact NMOs have had on cultivating generations of leaders in medicine, trainees may not identify opportunities for leadership development that are transferable to future careers in academic medicine.
Methods: We designed and implemented a dynamic 60-minute workshop with an interactive PowerPoint presentation, author-owned video testimonials (from past student leaders of NMOs), two case presentations, and reflection exercises.
Research progress of gut microbiome and diabetic nephropathy.
Front Med (Lausanne)
December 2024
Department of Nephrology, Urology & Nephrology Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, China.
Diabetic nephropathy is an important complication of diabetic microvascular injury, and it is also an important cause of end-stage renal disease. Its high prevalence and disability rate significantly impacts patients' quality of life while imposing substantial social and economic burdens. Gut microbiota affects host metabolism, multiple organ functions, and regulates host health throughout the life cycle.
View Article and Find Full Text PDFAssociation between the heart rate to temperature ratio and 28-day mortality in patients with heart failure in intensive care unit: a multicenter retrospective cohort study.
Front Med (Lausanne)
December 2024
Department of Clinical Laboratory, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang, China.
Background: Heart failure (HF) is a life-threatening condition with a high mortality rate. The precise relationship between the heart rate and temperature (HR/T) ratio and mortality in patients with HF remains unclear. This study aimed to investigate the relationship between the HR/T ratio and 28-day intensive care unit (ICU) mortality rates in patients with HF.
View Article and Find Full Text PDFTMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation.
Oncol Res
December 2024
Department of Rehabilitation, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530000, China.
Background: Transmembrane emp24 trafficking protein 3 (TMED3) is associated with the development of several tumors; however, whether TMED3 regulates the progression of prostate cancer remains unclear.
Materials And Methods: Short hairpin RNA was performed to repress TMED3 in prostate cancer cells (DU145 cells) and in a prostate cancer mice model to determine its function in prostate cancer and .
Results: In the present study, we found that TMED3 was highly expressed in prostate cancer cells.
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