The functional role of the primary motor cortex (M1) in the production of movement parameters, such as length, direction and force, is well known; however, whether M1 is associated with the parametric adjustments in the absolute timing dimension of the task remains unknown. Previous studies have not applied tasks and analyses that could separate the absolute (variant) and relative (invariant) dimensions. We applied transcranial direct current stimulation (tDCS) to M1 before motor practice to facilitate motor learning. A sequential key-pressing task was practiced with two goals: learning the relative timing dimension and learning the absolute timing dimension. All effects of the stimulation of M1 were observed only in the absolute dimension of the task. Mainly, the stimulation was associated with better performance in the transfer test in the absolute dimension. Taken together, our results indicate that M1 is an important area for learning the absolute timing dimension of a motor sequence.
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http://dx.doi.org/10.1016/j.physbeh.2016.03.025 | DOI Listing |
Front Pediatr
January 2025
Department of Anesthesiology, University of Wisconsin Foundation, Madison, WI, United States.
Global health prioritizes improving health and achieving equity in health for all people worldwide. It encompasses a wide range of efforts, including disease prevention and treatment, health promotion, healthcare delivery, and addressing health disparities across borders. Short-term medical and surgical missions often contribute to the global health landscape, especially in low and lower-middle income countries.
View Article and Find Full Text PDFChild Abuse Negl
January 2025
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA; Program in Neuroscience, Indiana University, Bloomington, IN, USA. Electronic address:
Background: Perinatal and childhood periods are sensitive windows of development wherein adversity exposure can result in disadvantageous outcomes. Data-driven dimensional approaches that appreciate the co-occurrence of adversities allow for extending beyond specificity (individual adversities) and cumulative risk (non-specific summation of adversities) approaches to understand how the type and timing of adversities affect outcomes.
Objective: With evolving recommendations on what should be important in adversity research, we sought to establish a data-driven framework that accounts for both type and timing of adversity by (1) replicating dimensions of childhood adversities, (2) determining whether perinatal adversities form unique dimensions and (3) identifying whether adversities during the perinatal and childhood periods overlap or remain distinct.
Epilepsy Behav
January 2025
Selçuk University, Medical Faculty, Department of Neurology, Konya, Turkey. Electronic address:
Objective: This study aimed to evaluate the impact of a computer-assisted rehabilitation program on self-management, cognitive function, and quality of life in people with epilepsy (PwE).
Methods: A randomized controlled trial was conducted with 44 PwE (22 intervention, 22 control) at a university hospital's neurology clinic. The intervention group received 12 sessions of the RehaCom program (45 min/session, twice a week for six weeks).
BMC Pregnancy Childbirth
January 2025
Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran.
Background: High-risk pregnancies are accompanied by significant complications for the mother, fetus, and baby if not controlled and received timely care. During home antenatal care, high-risk pregnant women can receive non-medical interventions by a home visitor.
Objective: This study's main aim was to explore care providers' perspectives regarding the home care program for high-risk pregnancies.
Sci Rep
January 2025
Deutsches Herzzentrum der Charité, Department of Congenital and Pediatric Heart Surgery, Augustenburger Platz 1, 13353, Berlin, Germany.
Limited magnetic resonance imaging (MRI) data on autograft dilatation following the Ross procedure in congenital cohorts presents challenges in understanding its evolution and impact on clinical outcomes. This study, spanning from February 2003 to December 2022, included patients under 40 years at the time of the Ross procedure, with MRI follow-ups assessing dimensions at key aortic sites. Among 307 patients, 132 MRIs were analyzed from 76 individuals, revealing that autograft z-scores increase primarily with time post-procedure (Coef.
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