Background: Aging-related muscle weakness is associated with increased risk of functional limitations and disability. This study examined the association between varying degrees of hand grip strength on functional ability in community-dwelling older adults.
Methods: Cross-sectional analysis of 4289 men and 5860 women ≥60 from 2006 and 2008 waves of the population-based Health and Retirement Study (HRS) were stratified by sex-specific grip strength tertiles (low, mid, high). Prevalence and adjusted odds of physical limitations (PL), and ADL/IADL limitation were calculated by sex, race/ethnicity and age group (60-69, 70-79, 80+). Models were weighted, adjusted for age, sex, race/ethnicity, education, smoking status, BMI, comorbidities and participation in physical activity.
Results: Prevalence of PL, ADL and IADL limitations were significantly lower among adults in the highest grip category as compared to those in the lowest grip category. Adjusted odds for PL OR 0.41[0.33,0.52]; ADL OR.51 [0.39,0.67], and IADL OR 0.47 [0.38-0.59] limitations were significantly lower among adults in the highest grip compared to the lowest grip category. However, notable differences were observed in the strength of these associations by gender, race and age group.
Conclusion: Demographic characteristics are important factors to consider for risk stratification and the development of effective grip strength training interventions for older adults.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.archger.2016.03.007 | DOI Listing |
Front Endocrinol (Lausanne)
January 2025
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Background: Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. However, the causal relationship remains uncertain. This study aims to verify whether glucosamine is causally associated with cognitive function and sarcopenia.
View Article and Find Full Text PDFAlthough current treatments for Duchenne Muscular Dystrophy (DMD) have proven to be effective in delaying myopathy, there remains a strong need to identify novel targets to develop additional therapies. Mitochondrial dysfunction is an early pathological feature of DMD. A fine balance of mitochondrial dynamics (fission and fusion) is crucial to maintain mitochondrial function and skeletal muscle health.
View Article and Find Full Text PDFPsychogeriatrics
January 2025
Healthcare Data Centre, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Background: Despite a wealth of literature on marital dissatisfaction and adverse health outcomes, little is known about the relationship between marital dissatisfaction and frailty in older adults.
Methods: This longitudinal study utilised the data of 11 174 individuals who participated in the biennial Korean Longitudinal Study of Ageing survey from 2006 to 2020 and were aged ≥45 during the initial wave. Frailty was measured using a frailty instrument, which utilised exhaustion, social isolation, and handgrip strength weakness.
Support Care Cancer
January 2025
S' Clinic, Guangzhou, 510000, China.
Purpose: This study aims to explore the effects of Tai Chi Chuan (TCC) on physical function, hematological metabolic biomarkers, sleep quality, and mental health in breast cancer patients.
Methods: This was a prospective clinical trial that involved 37 breast cancer patients who had completed surgery treatment. Participants' motor function, hematological examination, and self-rated questionnaire were assessed at the baseline and after the intervention.
Sci Rep
January 2025
Department of Preclinical Sciences, Pharmacology and Medical Diagnostics, Faculty of Medicine, Wroclaw University of Sciences and Technology, Wrocław, Poland.
With advancing age, progressive loss of muscle strength, as assessed by hand grip strength, may result in a poorer health-related quality of life. The aim of this study is to determine the associations of hand grip strength with quality of life among people aged 50-90 years from South West Poland. The study group comprised 1 446 people, including 351 men and 1 095 women, aged between 50 and 90 years.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!