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Investigation of an Outbreak of Equine Herpesvirus-1 Myeloencephalopathy in a Population of Aged Working Equids.
Viruses
December 2024
Carson Valley Large Animal Clinic, Gardnerville, NV 89460, USA.
The objective of this study was to describe an outbreak of equine herpesvirus-1 myeloencephalopathy (EHM) in a population of aged equids. The outbreak was linked to the introduction of five healthy non-resident horses 15 days prior to the first case of acute recumbency. This fulminant EHM outbreak was predisposed by the grouping of the 33 unvaccinated animals in two large pens with shared water and feed troughs.
View Article and Find Full Text PDFNew Fresnel lens loupe for nystagmus observation suitable for use by medical staff in emergency departments.
Int J Emerg Med
December 2024
Mejiro University Ear Institute Clinic, 320 Ukiya, Iwatsuki-ku, Saitama-shi, Saitama, 339-8501, Japan.
Background: Reduction of spontaneous nystagmus by fixation, a characteristic feature of peripheral nystagmus, is important for differentiating between peripheral and central vestibular disorders. In the emergency room, Frenzel goggles are recommended to observe spontaneous nystagmus for the differential diagnosis of acute vestibular syndrome. We developed a portable loupe with a Fresnel lens to observe nystagmus.
View Article and Find Full Text PDFCatch-Up Saccades in Vestibulo-Ocular Reflex Deficit: Contribution of Visual Information?
Ear Hear
December 2024
Institut national de la santé et de la recherche médicale, U1028, Centre National de Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Integrative Multisensory Perception and ACTion Team, Lyon, France.
Objectives: Catch-up saccades help to compensate for loss of gaze stabilization during rapid head rotation in case of vestibular deficit. While overt saccades observed after head rotation are obviously visually guided, some of these catch-up saccades occur with shorter latency while the head is still moving, anticipating the needed final eye position. These covert saccades seem to be generated based on the integration of multisensory inputs.
View Article and Find Full Text PDFA comatose vertebrobasilar occlusion patient recovering with bilateral hearing loss following full recanalization with mechanical thrombectomy.
Neuroradiol J
December 2024
Department of Neurology, Istanbul Aydin University, Istanbul, Turkey.
Article Synopsis
- * Despite successful mechanical thrombectomy (MT) and stenting achieving full recanalization, the patient showed poor recovery in hearing, with persistent bilateral SNHL remaining post-treatment.
- * The study underscores the complexity of neurological outcomes after vertebrobasilar occlusion, suggesting that while MT might alleviate other neurologic symptoms, its effectiveness on SNHL can vary greatly among patients.
Targeting sleep physiology to modulate glymphatic brain clearance.
Physiology (Bethesda)
November 2024
Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behavior, Nijmegen, Netherlands.
Article Synopsis
- Sleep is crucial for removing neurotoxic substances like amyloid-β from the brain, and poor sleep can lead to neurotoxins building up, risking neuron death and increasing the chances of neurodegenerative diseases like Alzheimer's and Parkinson's.
- There is a two-way relationship between sleep issues and neurodegeneration, indicating that sleep impairment may start affecting brain health long before symptoms show up.
- The review discusses methods to enhance sleep's restorative functions through sensory, transcranial, pharmacological, and behavioral interventions aimed at boosting brain clearance and preventing cognitive decline.
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