Cervical Length Screening in Asymptomatic Women at High Risk and Low Risk for Spontaneous Preterm Birth.

Clin Obstet Gynecol

*Department of Obstetrics & Gynecology, Virginia Hospital Center, Division of Maternal Fetal Medicine, Arlington, Virginia †Department of Obstetrics & Gynecology, Division of Maternal Fetal Medicine, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

Published: June 2016

Cervical length (CL) screening should be offered to singletons because there are interventions for those with a short CL. A transvaginal ultrasound (TVU) is the "gold standard" for CL. In singletons with prior spontaneous preterm birth, serial TVU CL screening is recommended between 16 and 23 6/7 weeks. Universal TVU CL screening between 18 and 24 weeks may be considered for low-risk singletons with the administration of vaginal progesterone for TVU CL≤20 mm; alternatively, transabdominal ultrasound CL screening may be considered with reflux to TVU CL screening for a transabdominal ultrasound CL<35 mm or inadequate visualization. CL screening is not recommended in multiples.

Download full-text PDF

Source
http://dx.doi.org/10.1097/GRF.0000000000000195DOI Listing

Publication Analysis

Top Keywords

tvu screening
12
cervical length
8
length screening
8
spontaneous preterm
8
preterm birth
8
transabdominal ultrasound
8
screening
6
tvu
5
screening asymptomatic
4
asymptomatic women
4

Similar Publications

This review evaluates the advances in the early detection and diagnosis of endometrial cancer (EC), emphasizing the growing importance of minimally invasive techniques and novel biomarkers. Current diagnostic protocols for EC rely heavily on invasive procedures such as transvaginal ultrasound (TVU), hysteroscopy, and endometrial biopsy, which, although effective, can be overly burdensome for patients and inefficient for asymptomatic or low-risk populations. As there is no consensus on EC screening in high-risk or general populations, recent studies have explored alternative methods using biofluids and genomic biomarkers to improve sensitivity and specificity and facilitate access for patients.

View Article and Find Full Text PDF

Ultrasonography in the diagnosis of pelvic vein insufficiency, a systematic review and meta-analysis.

Phlebology

January 2025

Division of Vascular Surgery - 2nd Department of Surgery, "G. Gennimatas" Hospital, Faculty of Medicine, School of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Objective: To perform a systematic review and meta-analysis to investigate the efficacy of ultrasonography in the diagnosis of pelvic vein insufficiency (PVI).

Results: Seven studies comprised of 802 patients were included. Of these studies, 5 utilised transvaginal ultrasound (TVU), 1 utilised transabdominal ultrasound (TAU) and 1 utilised both ultrasounds as diagnostic tool .

View Article and Find Full Text PDF

Second trimester cervical length screening, in a low-risk European population.

J Matern Fetal Neonatal Med

December 2025

Obstetrics Unit, Department of Medical and Surgical Sciences for Mothers, Children and Adults, University of Modena and Reggio Emilia, Modena, Italy.

Purpose: The aim of this work is to assess cervical length (CL) distribution in a low-risk population in order to evaluate the applicability of a possible universal CL screening in the second trimester, aimed at preventing preterm birth (PTB).

Methods: In a multicentric, prospective cohort study, singleton pregnant women attending second trimester anatomy scan between 18 + 0 to 22 + 6 weeks of gestation were eligible. Teenage pregnancy and women with previous PTB were excluded.

View Article and Find Full Text PDF

Risk-stratified CA125 screening integrating CA125 trajectories, trajectory-specific progression and transvaginal ultrasound for ovarian cancer.

J Ovarian Res

October 2024

Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, Tianjin, 300060, China.

Article Synopsis
  • CA125 is a commonly used biomarker for ovarian cancer screening, but its effectiveness is questioned due to issues like ineffective cut-off values and not accounting for changes over time in CA125 levels.
  • * This study analyzed data from the PLCO Trial, involving 28,456 women, to determine optimal CA125 cut-off values and examine the relationship between different patterns (trajectories) of CA125 levels and ovarian cancer risk.
  • * Results showed that certain CA125 trajectories significantly increased the risks of ovarian cancer incidence and mortality, with specific cut-off values identified for better screening performance over time.
View Article and Find Full Text PDF

Objective: It is challenging to accurately distinguish atypical endometrial hyperplasia (AEH) and endometrial cancer (EC) under routine transvaginal ultrasonic (TVU) detection. Our research aims to use the few-shot learning (FSL) method to identify non-atypical endometrial hyperplasia (NAEH), AEH, and EC based on limited TVU images.

Methods: The TVU images of pathologically confirmed NAEH, AEH, and EC patients (n = 33 per class) were split into the support set (SS, n = 3 per class) and the query set (QS, n = 30 per class).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!