AI Article Synopsis
- Exercise intensity can impact cognitive function and mood, leading to better mental health outcomes, but it can also have negative effects if taken to extremes.
- The concept of a hormetic-like biphasic dose-response explains how different levels of exercise can either benefit or harm individuals, highlighting the importance of training intensity.
- Recent research is exploring how adult hippocampal neurogenesis plays a role in these exercise-induced effects on cognition and mood, along with the molecular pathways involved.
Article Abstract
Exercise can make you smarter, happier and have more neurons depending on the dose (intensity) of the training program. It is well recognized that exercise protocols induce both positive and negative effects depending on the intensity of the exercise, among other key factors, a process described as a hormetic-like biphasic dose-response. However, no evidences have been reported till very recently about the biphasic response of some of the potential mediators of the exercise-induced actions. This hypothesis and theory will focus on the adult hippocampal neurogenesis (AHN) as a putative physical substrate for hormesis responses to exercise in the context of exercise-induced actions on cognition and mood, and on the molecular pathways which might potentially be mediating these actions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789405 | PMC |
| http://dx.doi.org/10.3389/fnins.2016.00093 | DOI Listing |
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