Recent developments in computed tomography (CT) technology have fulfilled the prerequisites for the clinical application of myocardial CT perfusion (CTP) imaging. The evaluation of myocardial perfusion by CT can be achieved by static or dynamic scan acquisitions. Although both approaches have proved clinically feasible, substantial barriers need to be overcome before its routine clinical application. The current review provides an outline of the current status of CTP imaging and also focuses on disparities between static and dynamic CTPs for the evaluation of myocardial blood flow.
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http://dx.doi.org/10.1093/ehjci/jew044 | DOI Listing |
Soft Matter
January 2025
Department of Physics, School of Advanced Sciences, Vellore Institute of Technology, Vellore, Tamil Nadu 632014, India.
We study the kinetics of vapor-liquid and vapor-solid phase separation of a hydrodynamics preserving three-dimensional one-component Lennard Jones system in the presence of an external gravitational field using extensive molecular dynamic simulation. A bicontinuous domain structure is formed when the homogeneous system near the critical density is quenched inside the coexistence region. In the absence of gravity, the domain morphology is statistically self-similar and the length scale grows as per the existing laws.
View Article and Find Full Text PDFSoft Matter
January 2025
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Microfluidic chips are powerful tools for investigating numerous variables including chemical and physical parameters on protein aggregation. This study investigated the aggregation of bovine serum albumin (BSA) in two different systems: a vial-based static system and a microfluidic chip-based dynamic system in which BSA aggregation was induced successfully. BSA aggregation induced in a microfluidic chip on a timescale of seconds enabled a dynamic investigation of the forces driving the aggregation process.
View Article and Find Full Text PDFAnim Cells Syst (Seoul)
January 2025
Department of Genome Medicine and Science, Gachon University College of Medicine, Incheon, Republic of Korea.
Dynamic modeling of cellular states has emerged as a pivotal approach for understanding complex biological processes such as cell differentiation, disease progression, and tissue development. This review provides a comprehensive overview of current approaches for modeling cellular state dynamics, focusing on techniques ranging from dynamic or static biomolecular network models to deep learning models. We highlight how these approaches integrated with various omics data such as transcriptomics, and single-cell RNA sequencing could be used to capture and predict cellular behavior and transitions.
View Article and Find Full Text PDFInt J Exerc Sci
December 2024
Department of Physical Therapy, Angelo State University, San Angelo, TX, USA.
Ankle sprains are common in female soccer players. Ankle injuries have the potential to impact balance control, which can further contribute to recurrent injuries. This study aimed to examine if female collegiate soccer players exhibited worse ankle stability and single-leg balance than female non-soccer players, and whether there was a correlation between ankle stability and single-leg balance.
View Article and Find Full Text PDFAesthetic Plast Surg
January 2025
Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No.1, Shuaifuyuan, Dongcheng District, Beijing, China.
Background: Perioral rejuvenation is challenging due to the lack of spatial anatomical understanding of the labiomandibular fold (LMF). The LMF's formation mechanism remains underexplored due to intricate relationships between musculature and subcutaneous structures. This study aimed to clarify the three-dimensional structures of the LMF using micro-computed tomography and histology.
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