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Association of plasma endocan levels with metabolic parameters and predictive value of endocan for the development of complications in patients with type 2 diabetes mellitus: An observational study.
Biomol Biomed
December 2024
Internal Medicine Clinic, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
The aim of the current research was to investigate the association between plasma endocan levels and metabolic control parameters, as well as to evaluate its predictive value for clinical complications in patients with type 2 diabetes mellitus (DMT2). A total of 100 DMT2 patients participated in this prospective observational study. Plasma endocan levels were significantly elevated in DMT2 patients with HbA1c > 7% (1.
View Article and Find Full Text PDFRelation of Endocan Serum Levels with Patient Characteristics and Morphological Features of Uterine Fibroids: A Case-Control Study.
Gynecol Obstet Invest
November 2024
Gynecology and Obstetrics Departments, Ankara City Hospital, Ankara, Turkey.
Objectives: This study aimed to compare the serum endocan levels of patients with uterine fibroids and the healthy control group.
Design: A case-control study was designed. Participants/Materials: The study group includes women diagnosed with uterine fibroids, and the control group includes healthy women.
Serum endocan (ESM-1) as diagnostic and prognostic biomarker in Multisystem inflammatory syndrome in children (MIS-C).
Cytokine
December 2024
Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Naples, Italy; CEINGE-Biotecnologie Avanzate S.c.a.r.l., Naples, Italy.
Article Synopsis
- Endothelial-cell-specific molecule-1 (ESM-1), also known as endocan, is identified as a significant biomarker for inflammation and cardiovascular risk in COVID-19 patients, particularly in the context of Multisystem Inflammatory Syndrome in children (MIS-C).
- In a study comparing ESM-1 levels between MIS-C patients and healthy controls, MIS-C patients showed significantly higher levels of ESM-1, suggesting its potential diagnostic value.
- The research indicates that ESM-1 not only correlates with other inflammatory markers but is also associated with cardiac complications, highlighting its role in assessing cardiovascular risks in MIS-C patients and aiding in treatment strategies.
Biochemical markers and carotid intima-media thickness in relation to cardiovascular risk in young women.
Sci Rep
October 2024
Department of Endocrinology and Metabolism, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
Cardiovascular disease (CVD) is a major cause of death in the female population. The current study aimed to examine the relationship between CVD risk and novel endothelial dysfunction biomarkers [i.e.
View Article and Find Full Text PDFEndocan, a novel glycoprotein with multiple biological activities, may play important roles in neurological diseases.
Front Aging Neurosci
September 2024
Department of Neurology, Shengjing Hospital of China Medical University, China Medical University, Shenyang, China.
Article Synopsis
- Endothelial cell specific-1 (endocan) is a soluble protein secreted by endothelial cells, linked to cancer development, cardiovascular issues, autoimmune diseases, and sepsis.
- Its biological functions depend on specific regions in its structure, with elevated levels indicating endothelial activation and dysfunction.
- The review explores endocan's structure, functions, and potential clinical significance in neurological disorders.
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