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In recent years, the importance of working holistically on the global One Health and One Welfare agendas has become evident. The success of these policies in addressing shared challenges depends on a science-based global strategy for animal welfare that allows local efforts to resolve conflicts related to how human beings take advantage of natural resources, including domestic and wild animals. These policies need to be developed jointly by the World Organisation for Animal Health, the World Health Organization and the Food and Agriculture Organization of the United Nations and in line with the United Nations' Sustainable Development Goals.
View Article and Find Full Text PDFSticky Polyelectrolyte Shield for Enhancing Biological Half-Life of Growth Factors.
ACS Appl Mater Interfaces
December 2024
Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Delivery of secretomes, which includes growth factors, cytokines, and mRNA, is critical in regenerative medicine for cell-to-cell communication. However, the harsh in vivo environment presents significant challenges for secretome delivery. Proteolytic enzymes shorten secretomes' half-lives, and secretomes tend to rapidly diffuse at defect sites.
View Article and Find Full Text PDFToward a transdisciplinary and unifying definition of legacy phosphorus.
J Environ Qual
December 2024
Lancaster Environment Centre, Lancaster University, Lancaster, UK.
Legacy phosphorus (P) is a concept advanced by Dr. Andrew Sharpley and colleagues that was originally applied to the persistence of anthropogenic signatures in watersheds, and it has since been adopted in a diversity of settings to help guide the science and management of P. Following Sharpley's example to develop consensus-based science, we considered contrasting perspectives on legacy P and defined legacy P as those stores within the environment that arise from historic human activity excluding "natural" or "background" geogenic sources.
View Article and Find Full Text PDFNarrative Preparedness: Policy-Makers Must Engage With People's Values and Experiences to Ensure Effective Implementation of Interventions in Health Emergencies Comment on "Health Preparedness and Narrative Rationality: A Call for Narrative Preparedness".
Int J Health Policy Manag
December 2024
Institute of Development Studies, University of Sussex, Brighton, UK.
Engebretsen and Baker's conceptual paper "" advocates for the adoption of narrative preparedness in addition to health preparedness, emphasising the importance of engaging with people's stories and values during health emergencies. This ensures that policy-makers and health authorities gain the trust of communities as there is evidence this leads to improved outcomes. Their key argument is that science cannot be used effectively in policy unless it makes sense to people and is presented in a way that resonates with their values.
View Article and Find Full Text PDFDigital therapeutics in Japan: Present and future directions.
J Cardiol
November 2024
College of Transdisciplinary Sciences for Innovation, Kanazawa University, Kanazawa, Japan; Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan; Frontier Institute of Tourism Sciences, Kanazawa University, Kanazawa, Japan; CureApp Institute, Karuizawa, Japan. Electronic address:
Digital therapeutics (DTx) represent an innovative approach to healthcare, leveraging software applications (apps) delivered through digital devices to treat medical conditions. This review focuses on three DTx apps approved in Japan, targeting nicotine dependence, hypertension, and insomnia. CureApp SC, the DTx system for nicotine dependence, comprises a patient smartphone app, an Internet of Things device for exhaled carbon monoxide measurement, and a Web-based physician app.
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